Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADU46779.1Transcriptional regulator, GntR family; COGs: COG1725 transcriptional regulator protein; InterPro IPR000524; KEGG: nfa:nfa49100 putative transcriptional regulator; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Putative transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family. (125 aa)    
Predicted Functional Partners:
pyrD
Dihydroorotate oxidase A; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
       0.655
ADU49153.1
Transcriptional regulator, HxlR family; COGs: COG1733 transcriptional regulator protein; InterPro IPR002577; KEGG: nfa:nfa24980 putative transcriptional regulator; PFAM: helix-turn-helix HxlR type; SPTR: Putative transcriptional regulator; PFAM: HxlR-like helix-turn-helix.
   
    0.646
ADU48634.1
Zinc uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: mmi:MMAR_3669 zinc uptake regulation protein Zur; PFAM: ferric-uptake regulator; SPTR: Zinc uptake regulation protein Zur; PFAM: Ferric uptake regulator family; Belongs to the Fur family.
  
    0.624
ADU47824.1
Protein of unknown function DUF179; COGs: COG1678 Putative transcriptional regulator protein; InterPro IPR003774; KEGG: kra:Krad_3774 hypothetical protein; PFAM: protein of unknown function DUF179; SPTR: UPF0301 protein Krad_3774; PFAM: Uncharacterized ACR, COG1678.
   
    0.607
ADU48766.1
KEGG: cmi:CMM_1413 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.577
ADU49281.1
Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR017685; KEGG: xce:Xcel_2242 transcriptional regulator, LysR family; PFAM: regulatory protein LysR; SPTR: Transcriptional regulator, LysR family; TIGRFAM: transcriptional regulator, ArgP family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; TIGRFAM: transcriptional regulator, ArgP family.
   
  
 0.576
ADU47946.1
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: gob:Gobs_0866 silent information regulator protein Sir2; PFAM: Silent information regulator protein Sir2; SPTR: Putative SIR2-like regulatory protein; PFAM: Sir2 family.
  
    0.571
ADU46774.1
Transcriptional repressor, CopY family; COGs: COG3682 transcriptional regulator protein; InterPro IPR005650; KEGG: kse:Ksed_01860 predicted transcriptional regulator; PFAM: Penicillinase repressor; SPTR: Transcriptional regulator-like protein; PFAM: Penicillinase repressor.
  
    0.511
ADU46778.1
COGs: COG1271 Cytochrome bd-type quinol oxidase subunit 1; InterPro IPR002585; KEGG: nca:Noca_0942 cytochrome bd ubiquinol oxidase, subunit I; PFAM: cytochrome bd ubiquinol oxidase subunit I; SPTR: Cytochrome d ubiquinol oxidase subunit I; PFAM: Bacterial Cytochrome Ubiquinol Oxidase.
       0.503
ADU46775.1
ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC; COGs: COG4987 ABC-type transport system involved in cytochrome bd biosynthesis fused ATPase and permease components; InterPro IPR003439: IPR014223: IPR003593: IPR017940; KEGG: kse:Ksed_01870 cysteine export CydDC family ABC transporter permease subunit/ATP-binding protein CydC; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Putative ABC transporter ATP-binding protein; TIGRFAM: ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC; PFAM: ABC tran [...]
       0.488
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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