Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU46788.1Protein of unknown function DUF58; COGs: COG1721 conserved hypothetical protein (some members contain a von Willebrand factor type A (vWA) domain); InterPro IPR002881; KEGG: nca:Noca_3911 hypothetical protein; PFAM: protein of unknown function DUF58; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF58. (431 aa)    
Predicted Functional Partners:
ADU46790.1
KEGG: nca:Noca_3909 secreted protein; SPTR: Secreted protein.
 
  
 0.956
ADU46791.1
KEGG: amd:AMED_1140 hypothetical protein; SPTR: Putative integral membrane protein.
 
  
 0.956
ADU46792.1
KEGG: mul:MUL_4272 hypothetical protein; SPTR: Putative integral membrane protein; PFAM: Membrane domain of glycerophosphoryl diester phosphodiesterase.
 
     0.937
ADU46789.1
ATPase associated with various cellular activities AAA_3; COGs: COG0714 MoxR-like ATPase; InterPro IPR011703: IPR016366: IPR003593; KEGG: gbr:Gbro_4821 ATPase associated with various cellular activities AAA_3; PFAM: ATPase associated with various cellular activities AAA_3; SMART: AAA ATPase; SPTR: Putative regulatory protein; PFAM: ATPase family associated with various cellular activities (AAA).
 
  
 0.922
ADU46787.1
Protein of unknown function DUF95 transmembrane; COGs: COG1300 membrane protein; InterPro IPR002798; KEGG: nca:Noca_3912 integral membrane protein; PFAM: protein of unknown function DUF95 transmembrane; SPTR: Putative membrane protein; manually curated; PFAM: Integral membrane protein DUF95.
 
  
 0.808
ADU46786.1
COGs: COG1714 membrane protein/domain; InterPro IPR010432; KEGG: gbr:Gbro_4825 RDD domain containing protein; PFAM: RDD domain containing protein; SPTR: Possible conserved membrane protein; PFAM: RDD family.
 
    0.789
ADU46794.1
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176: IPR006108: IPR006180; KEGG: kse:Ksed_01910 3-hydroxyacyl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; SPTR: 3-hydroxyacyl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
       0.581
ADU46793.1
Phenylacetic acid degradation protein PaaD; COGs: COG2050 Uncharacterized protein possibly involved in aromatic compounds catabolism; InterPro IPR006683: IPR003736: IPR011973; KEGG: kfl:Kfla_6849 phenylacetic acid degradation protein PaaD; PFAM: thioesterase superfamily protein; SPTR: Probable phenylacetic acid degradation protein; TIGRFAM: phenylacetic acid degradation protein PaaD; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1; phenylacetic acid degradation protein PaaD.
       0.578
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
     
 0.473
ADU47896.1
ATPase associated with various cellular activities AAA_3; COGs: COG0714 MoxR-like ATPase; InterPro IPR016366: IPR011703; KEGG: nca:Noca_1478 ATPase; PFAM: ATPase associated with various cellular activities AAA_3; SPTR: ATPase associated with various cellular activities, AAA_3; PFAM: ATPase family associated with various cellular activities (AAA).
 
  
 0.472
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.