STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU46793.1Phenylacetic acid degradation protein PaaD; COGs: COG2050 Uncharacterized protein possibly involved in aromatic compounds catabolism; InterPro IPR006683: IPR003736: IPR011973; KEGG: kfl:Kfla_6849 phenylacetic acid degradation protein PaaD; PFAM: thioesterase superfamily protein; SPTR: Probable phenylacetic acid degradation protein; TIGRFAM: phenylacetic acid degradation protein PaaD; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1; phenylacetic acid degradation protein PaaD. (143 aa)    
Predicted Functional Partners:
ADU48697.1
phenylacetate-CoA oxygenase, PaaJ subunit; COGs: COG2151 metal-sulfur cluster biosynthetic protein; InterPro IPR011883: IPR002744; KEGG: kse:Ksed_09320 phenylacetate-CoA oxygenase, PaaJ subunit; PFAM: protein of unknown function DUF59; SPTR: Phenylacetate-CoA oxygenase, PaaJ subunit; TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit; manually curated; PFAM: Domain of unknown function DUF59; TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit.
 
 
 0.983
ADU48699.1
phenylacetate-CoA oxygenase, PaaH subunit; COGs: COG3460 Uncharacterized protein of phenylacetate metabolism; InterPro IPR009359; KEGG: kse:Ksed_09300 phenylacetate-CoA oxygenase, PaaH subunit; PFAM: phenylacetic acid degradation B; SPTR: Phenylacetate-CoA oxygenase, PaaH subunit; TIGRFAM: phenylacetate-CoA oxygenase, PaaH subunit; PFAM: Phenylacetic acid degradation B; TIGRFAM: phenylacetate-CoA oxygenase, PaaH subunit.
 
 
 0.983
ADU48698.1
phenylacetate-CoA oxygenase, PaaI subunit; COGs: COG3396 conserved hypothetical protein; InterPro IPR011882: IPR007814; KEGG: kse:Ksed_09310 phenylacetate-CoA oxygenase, PaaI subunit; PFAM: phenylacetic acid catabolic family protein; SPTR: Phenylacetate-CoA oxygenase, PaaI subunit; TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit; PFAM: Phenylacetic acid catabolic protein; TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit.
 
 
 0.982
ADU48700.1
phenylacetate-CoA oxygenase, PaaG subunit; COGs: COG3396 conserved hypothetical protein; InterPro IPR011881: IPR007814; KEGG: kse:Ksed_09290 phenylacetate-CoA oxygenase subunit PaaA; PFAM: phenylacetic acid catabolic family protein; SPTR: Phenylacetate-CoA oxygenase, PaaG subunit; TIGRFAM: phenylacetate-CoA oxygenase, PaaG subunit; PFAM: Phenylacetic acid catabolic protein; TIGRFAM: phenylacetate-CoA oxygenase, PaaG subunit.
 
 
 0.982
ADU48696.1
phenylacetate-CoA oxygenase/reductase, PaaK subunit; COGs: COG1018 Flavodoxin reductase (ferredoxin-NADPH reductase) family 1; InterProIPR011884: IPR006058: IPR001041: IPR017927: IPR 008333: IPR001433: IPR001709: IPR001221; KEGG: kse:Ksed_09330 phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; SPTR: Phenylacetate-CoA oxygenase/reductase, PaaK subunit; TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Oxidoreductas [...]
 
 
  0.978
ADU46781.1
phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).
 
 
 0.976
ADU46907.1
AMP-dependent synthetase and ligase; COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: chl:Chy400_1182 coenzyme F390 synthetase-like protein; PFAM: AMP-dependent synthetase and ligase; SPTR: Coenzyme F390 synthetase-like protein; PFAM: AMP-binding enzyme.
 
 
 0.944
ADU49329.1
Amidase; COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; InterPro IPR000120: IPR020556; KEGG: rop:ROP_37880 putative amidase; PFAM: Amidase; SPTR: Putative amidase; PFAM: Amidase; Belongs to the amidase family.
    
  0.900
ADU46794.1
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176: IPR006108: IPR006180; KEGG: kse:Ksed_01910 3-hydroxyacyl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; SPTR: 3-hydroxyacyl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
 
  
 0.871
ADU46795.1
Phenylacetic acid degradation protein paaN; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR011975; KEGG: kse:Ksed_01930 phenylacetic acid degradation protein PaaN; PFAM: Aldehyde Dehydrogenase; SPTR: Phenylacetic acid degradation protein paaN; TIGRFAM: phenylacetic acid degradation protein paaN; PFAM: Aldehyde dehydrogenase family; TIGRFAM: phenylacetic acid degradation protein paaN.
 
   
 0.775
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.