STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pfkAPyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (362 aa)    
Predicted Functional Partners:
ADU48205.1
COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672; KEGG: ach:Achl_1836 phosphoglucose isomerase (PGI); PFAM: phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
  
 0.985
ADU49748.1
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
 
 
 0.962
ADU47641.1
Ketose-bisphosphate aldolase class-II; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: ach:Achl_0507 ketose-bisphosphate aldolase class-II; PFAM: ketose-bisphosphate aldolase class-II; SPTR: Ketose-bisphosphate aldolase class-II; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases.
 
 
 0.952
ADU48159.1
COGs: COG0469 Pyruvate kinase; InterPro IPR015793: IPR018209: IPR015794: IPR001697; KEGG: cfl:Cfla_1980 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.940
ADU49744.1
COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR002173: IPR017583: IPR011611; KEGG: sen:SACE_2273 putative 6-phosphofructokinase; PFAM: PfkB domain protein; PRIAM: 1-phosphofructokinase; SPTR: Putative 6-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: 1-phosphofructokinase; hexose kinase, 1-phosphofructokinase family.
  
  
 0.936
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
  
 0.934
ADU48207.1
Transketolase; COGs: COG0021 Transketolase; InterProIPR005474: IPR020826: IPR005475: IPR005476: IPR 005478; KEGG: sgr:SGR_4907 transketolase; PFAM: Transketolase domain-containing protein; Transketolase central region; SPTR: Putative transketolase; TIGRFAM: transketolase; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast; Belongs to the transketolase family.
  
 0.934
ADU49195.1
Fructose-1,6-bisphosphatase, class II; COGs: COG1494 Fructose-1 6-bisphosphatase/sedoheptulose 1 7-bisphosphatase and related protein; InterPro IPR004464; KEGG: kfl:Kfla_5587 fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; PRIAM: Fructose-bisphosphatase; SPTR: Putative fructose-1,6-bisphosphatase II; TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: Bacterial fructose-1,6-bisphosphatase, glpX-encoded; TIGRFAM: fructose-1,6-bisphosphatase, class II.
   
 
 0.932
ADU49196.1
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611: IPR002173; KEGG: tpr:Tpau_0525 PfkB domain protein; PFAM: PfkB domain protein; SPTR: Putative uncharacterized protein; PFAM: pfkB family carbohydrate kinase.
  
 0.916
ADU49018.1
Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase; InterPro IPR019490: IPR006162; KEGG: kra:Krad_3839 putative transcriptional regulator, RpiR family; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; SPTR: Putative uncharacterized protein; PFAM: Bacterial phospho-glucose isomerase C-terminal region.
    
 0.908
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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