STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU46843.1COGs: COG2124 Cytochrome P450; InterPro IPR001128: IPR017972: IPR002397; KEGG: gob:Gobs_1911 cytochrome P450; PFAM: cytochrome P450; SPTR: Cytochrome P450; PFAM: Cytochrome P450. (444 aa)    
Predicted Functional Partners:
ADU47406.1
UDP-glucuronosyl/UDP-glucosyltransferase; COGs: COG1819 Glycosyl transferase related to UDP-glucuronosyltransferase; InterPro IPR002213; KEGG: nml:Namu_2594 UDP-glucuronosyl/UDP-glucosyltransferase; PFAM: UDP-glucuronosyl/UDP-glucosyltransferase; SPTR: UDP-glucuronosyl/UDP-glucosyltransferase; PFAM: UDP-glucoronosyl and UDP-glucosyl transferase; TIGRFAM: glycosyltransferase, MGT family.
 
 
 0.883
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
    
 0.864
rplF
LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.852
ADU46842.1
COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: kse:Ksed_22440 predicted hydrolase or acyltransferase of alpha/beta superfamily; PFAM: alpha/beta hydrolase fold; SPTR: Alpha/beta hydrolase fold protein; PFAM: alpha/beta hydrolase fold.
 
 
 0.850
acpP
Phosphopantetheine-binding protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 0.820
ADU47946.1
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: gob:Gobs_0866 silent information regulator protein Sir2; PFAM: Silent information regulator protein Sir2; SPTR: Putative SIR2-like regulatory protein; PFAM: Sir2 family.
    
  0.773
ADU48696.1
phenylacetate-CoA oxygenase/reductase, PaaK subunit; COGs: COG1018 Flavodoxin reductase (ferredoxin-NADPH reductase) family 1; InterProIPR011884: IPR006058: IPR001041: IPR017927: IPR 008333: IPR001433: IPR001709: IPR001221; KEGG: kse:Ksed_09330 phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; SPTR: Phenylacetate-CoA oxygenase/reductase, PaaK subunit; TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Oxidoreductas [...]
  
 0.737
ADU49552.1
Oxidoreductase FAD/NAD(P)-binding domain protein; COGs: COG1018 Flavodoxin reductase (ferredoxin-NADPH reductase) family 1; InterProIPR001041: IPR017927: IPR001221: IPR008333: IPR 001433; KEGG: art:Arth_0194 oxidoreductase FAD/NAD(P)-binding subunit; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; ferredoxin; SPTR: Oxidoreductase FAD/NAD(P)-binding domain protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain.
  
 0.737
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
    
 0.735
ADU46798.1
Putative exonuclease; COGs: COG0419 ATPase involved in DNA repair; KEGG: cfl:Cfla_0124 putative exonuclease; SPTR: Putative exonuclease; TIGRFAM: exonuclease SbcC.
    
 0.730
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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