STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU46849.1COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160; KEGG: nca:Noca_2092 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Aldehyde dehydrogenase (NAD(+)); PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (507 aa)    
Predicted Functional Partners:
ADU46850.1
Protein of unknown function DUF779; COGs: COG3564 conserved hypothetical protein; InterPro IPR008497; KEGG: sen:SACE_2914 hypothetical protein; PFAM: protein of unknown function DUF779; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF779).
 
    0.949
ADU46915.1
COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: cai:Caci_4507 acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Acetate/CoA ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme.
   
 0.929
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.929
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
 
 0.918
ADU47426.1
Alcohol dehydrogenase zinc-binding domain protein; COGs: COG1064 Zn-dependent alcohol dehydrogenase; InterPro IPR013154: IPR013149: IPR002328; KEGG: mjl:Mjls_1690 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: Alcohol dehydrogenase, zinc-binding domain protein; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase.
  
 
 0.909
ADU47738.1
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: bcv:Bcav_0211 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Putative aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family.
 
    
0.909
ADU47739.1
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160; KEGG: bcv:Bcav_0209 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Putative aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.909
ADU48398.1
Zinc-binding alcohol dehydrogenase family protein; COGs: COG1064 Zn-dependent alcohol dehydrogenase; InterPro IPR013154: IPR013149: IPR014187; KEGG: sro:Sros_4103 putative alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; SPTR: Putative alcohol dehydrogenase; TIGRFAM: zinc-binding alcohol dehydrogenase family protein; PFAM: Alcohol dehydrogenase GroES-like domain; TIGRFAM: zinc-binding alcohol dehydrogenase family protein.
 
 
 0.909
ADU49539.1
Alcohol dehydrogenase GroES domain protein; COGs: COG1064 Zn-dependent alcohol dehydrogenase; InterPro IPR013154: IPR013149: IPR002328; KEGG: art:Arth_3087 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; SPTR: Alcohol dehydrogenase GroES domain protein; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase.
 
 
 0.909
ADU50030.1
COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR012133: IPR000262: IPR008259; KEGG: sen:SACE_6523 lactate 2-monooxygenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: Lactate 2-monooxygenase; PFAM: FMN-dependent dehydrogenase.
 
 
 
 0.909
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.