Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADU46874.1KEGG: xce:Xcel_3445 hypothetical protein; SPTR: Putative uncharacterized protein. (326 aa)    
Predicted Functional Partners:
ADU47303.1
Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001932: IPR007895: IPR010822: IPR003594; KEGG: gob:Gobs_0116 multi-sensor signal transduction histidine kinase; PFAM: Stage II sporulation protein E; MASE1 domain protein; ATP-binding region ATPase domain protein; SMART: protein phosphatase 2C domain protein; SPTR: Multi-sensor signal transduction histidine kinase; PFAM: Stage II sporulation protein E (SpoIIE); MASE1.
  
 
 0.932
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.776
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.776
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.776
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.775
ADU49393.1
ATP-binding region ATPase domain protein; InterPro IPR003018: IPR003594: IPR018247; KEGG: cai:Caci_4163 putative PAS/PAC sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; SPTR: PAS/PAC sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
 
 0.714
ADU49002.1
SAF domain protein; InterPro IPR013974; KEGG: cfl:Cfla_2320 hypothetical protein; PFAM: SAF domain protein; SPTR: Putative uncharacterized protein.
  
  
 0.706
ADU46847.1
KEGG: kfl:Kfla_3734 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.604
ADU48622.1
KEGG: ske:Sked_14030 hypothetical protein; SPTR: DNA primase.
  
  
 0.589
ADU49418.1
M6 family metalloprotease domain protein; COGs: COG4412 conserved hypothetical protein; InterPro IPR008757: IPR017683; KEGG: tbi:Tbis_2142 M6 family metalloprotease domain-containing protein; PFAM: peptidase M6 immune inhibitor A; SPTR: Putative secreted protease; TIGRFAM: M6 family metalloprotease domain protein; PFAM: Immune inhibitor A peptidase M6; TIGRFAM: M6 family metalloprotease domain.
  
     0.568
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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