Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ADU46907.1AMP-dependent synthetase and ligase; COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: chl:Chy400_1182 coenzyme F390 synthetase-like protein; PFAM: AMP-dependent synthetase and ligase; SPTR: Coenzyme F390 synthetase-like protein; PFAM: AMP-binding enzyme. (416 aa)    
Predicted Functional Partners:
ADU46909.1
COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR000709; KEGG: rca:Rcas_0542 ABC-type branched-chain amino acid transport systems periplasmic component-like protein; SPTR: ABC-type branched-chain amino acid transport systems periplasmic component-like protein.
 
    0.945
ADU46908.1
Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family; COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: chl:Chy400_1183 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter.
 
    0.933
ADU46912.1
AMP-dependent synthetase and ligase; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873: IPR020845; KEGG: rrs:RoseRS_0623 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme.
 
    0.891
ADU46913.1
Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family; COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439: IPR003593; KEGG: rrs:RoseRS_0622 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter.
 
    0.850
ADU46910.1
Amino acid/amide ABC transporter membrane protein 2, HAAT family; COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: chl:Chy400_1185 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component.
 
    0.797
ADU46911.1
Amino acid/amide ABC transporter membrane protein 1, HAAT family; COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: chl:Chy400_1186 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component.
 
    0.720
ADU47944.1
Uncharacterized peroxidase-related enzyme; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
   
 0.611
ADU46914.1
Transcriptional regulator, IclR family; COGs: COG1414 Transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: rop:ROP_71890 putative IclR family transcriptional regulator; PFAM: regulatory protein IclR; SMART: regulatory protein IclR; SPTR: Putative IclR family transcriptional regulator; PFAM: IclR helix-turn-helix domain.
 
    0.512
ADU49556.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896: IPR011895: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017900; KEGG: mmi:MMAR_3408 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; TIGRFAM [...]
  
  
 0.476
ADU46793.1
Phenylacetic acid degradation protein PaaD; COGs: COG2050 Uncharacterized protein possibly involved in aromatic compounds catabolism; InterPro IPR006683: IPR003736: IPR011973; KEGG: kfl:Kfla_6849 phenylacetic acid degradation protein PaaD; PFAM: thioesterase superfamily protein; SPTR: Probable phenylacetic acid degradation protein; TIGRFAM: phenylacetic acid degradation protein PaaD; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1; phenylacetic acid degradation protein PaaD.
 
  
 0.462
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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