Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADU46912.1AMP-dependent synthetase and ligase; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873: IPR020845; KEGG: rrs:RoseRS_0623 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (678 aa)    
Predicted Functional Partners:
ADU46913.1
Amino acid/amide ABC transporter ATP-binding protein 1, HAAT family; COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439: IPR003593; KEGG: rrs:RoseRS_0622 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter.
 
    0.943
ADU46910.1
Amino acid/amide ABC transporter membrane protein 2, HAAT family; COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: chl:Chy400_1185 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component.
 
    0.918
ADU46907.1
AMP-dependent synthetase and ligase; COGs: COG1541 Coenzyme F390 synthetase; InterPro IPR000873; KEGG: chl:Chy400_1182 coenzyme F390 synthetase-like protein; PFAM: AMP-dependent synthetase and ligase; SPTR: Coenzyme F390 synthetase-like protein; PFAM: AMP-binding enzyme.
 
    0.891
ADU46909.1
COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR000709; KEGG: rca:Rcas_0542 ABC-type branched-chain amino acid transport systems periplasmic component-like protein; SPTR: ABC-type branched-chain amino acid transport systems periplasmic component-like protein.
 
    0.889
ADU46908.1
Amino acid/amide ABC transporter ATP-binding protein 2, HAAT family; COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: chl:Chy400_1183 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter.
 
    0.880
ADU46911.1
Amino acid/amide ABC transporter membrane protein 1, HAAT family; COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: chl:Chy400_1186 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transport system / permease component.
 
    0.880
ADU47746.1
Biotin carboxyl carrier protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR005481: IPR005479: IPR005482: IPR000089: IPR 001882: IPR011761: IPR011764; KEGG: kse:Ksed_08190 acetyl/propionyl-CoA carboxylase, alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: Putative acyl-CoA carboxylase, alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-te [...]
    
 0.809
ADU47762.1
COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022: IPR011762: IPR011763: IPR000438; KEGG: kfl:Kfla_1439 carboxyl transferase; PFAM: carboxyl transferase; SPTR: Propionyl-CoA carboxylase complex B subunit; PFAM: Carboxyl transferase domain.
    
  0.803
ADU47928.1
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: nml:Namu_4653 hypothetical protein; PFAM: AMP-dependent synthetase and ligase; SPTR: Putative uncharacterized protein; PFAM: AMP-binding enzyme.
 
 
 0.747
ADU48729.1
AMP-dependent synthetase and ligase; COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR020845: IPR018294: IPR000873; KEGG: kfl:Kfla_2400 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Putative long-chain fatty-acid CoA ligase; PFAM: AMP-binding enzyme.
  
  
 
0.686
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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