| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADU46914.1 | ADU46915.1 | Intca_0365 | Intca_0366 | Transcriptional regulator, IclR family; COGs: COG1414 Transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: rop:ROP_71890 putative IclR family transcriptional regulator; PFAM: regulatory protein IclR; SMART: regulatory protein IclR; SPTR: Putative IclR family transcriptional regulator; PFAM: IclR helix-turn-helix domain. | COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: cai:Caci_4507 acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Acetate/CoA ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme. | 0.821 |
| ADU46914.1 | ADU46916.1 | Intca_0365 | Intca_0367 | Transcriptional regulator, IclR family; COGs: COG1414 Transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: rop:ROP_71890 putative IclR family transcriptional regulator; PFAM: regulatory protein IclR; SMART: regulatory protein IclR; SPTR: Putative IclR family transcriptional regulator; PFAM: IclR helix-turn-helix domain. | COGs: COG2132 Putative multicopper oxidase; InterPro IPR017909: IPR011707: IPR011706: IPR002355; KEGG: sli:Slin_6866 bilirubin oxidase; PFAM: multicopper oxidase type 3; multicopper oxidase type 2; SPTR: Bilirubin oxidase; PFAM: Multicopper oxidase. | 0.445 |
| ADU46914.1 | argS | Intca_0365 | Intca_0368 | Transcriptional regulator, IclR family; COGs: COG1414 Transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: rop:ROP_71890 putative IclR family transcriptional regulator; PFAM: regulatory protein IclR; SMART: regulatory protein IclR; SPTR: Putative IclR family transcriptional regulator; PFAM: IclR helix-turn-helix domain. | COGs: COG0018 Arginyl-tRNA synthetase; InterProIPR005148: IPR015945: IPR008909: IPR001278: IPR 001412; KEGG: tfu:Tfu_0269 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; arginyl tRNA synthetase domain protein; DALR anticodon binding domain protein; PRIAM: Arginine--tRNA ligase; SPTR: Arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase. | 0.427 |
| ADU46915.1 | ADU46914.1 | Intca_0366 | Intca_0365 | COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: cai:Caci_4507 acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Acetate/CoA ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme. | Transcriptional regulator, IclR family; COGs: COG1414 Transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: rop:ROP_71890 putative IclR family transcriptional regulator; PFAM: regulatory protein IclR; SMART: regulatory protein IclR; SPTR: Putative IclR family transcriptional regulator; PFAM: IclR helix-turn-helix domain. | 0.821 |
| ADU46915.1 | ADU46916.1 | Intca_0366 | Intca_0367 | COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: cai:Caci_4507 acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Acetate/CoA ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme. | COGs: COG2132 Putative multicopper oxidase; InterPro IPR017909: IPR011707: IPR011706: IPR002355; KEGG: sli:Slin_6866 bilirubin oxidase; PFAM: multicopper oxidase type 3; multicopper oxidase type 2; SPTR: Bilirubin oxidase; PFAM: Multicopper oxidase. | 0.435 |
| ADU46915.1 | argS | Intca_0366 | Intca_0368 | COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: cai:Caci_4507 acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Acetate/CoA ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme. | COGs: COG0018 Arginyl-tRNA synthetase; InterProIPR005148: IPR015945: IPR008909: IPR001278: IPR 001412; KEGG: tfu:Tfu_0269 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; arginyl tRNA synthetase domain protein; DALR anticodon binding domain protein; PRIAM: Arginine--tRNA ligase; SPTR: Arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase. | 0.427 |
| ADU46916.1 | ADU46914.1 | Intca_0367 | Intca_0365 | COGs: COG2132 Putative multicopper oxidase; InterPro IPR017909: IPR011707: IPR011706: IPR002355; KEGG: sli:Slin_6866 bilirubin oxidase; PFAM: multicopper oxidase type 3; multicopper oxidase type 2; SPTR: Bilirubin oxidase; PFAM: Multicopper oxidase. | Transcriptional regulator, IclR family; COGs: COG1414 Transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: rop:ROP_71890 putative IclR family transcriptional regulator; PFAM: regulatory protein IclR; SMART: regulatory protein IclR; SPTR: Putative IclR family transcriptional regulator; PFAM: IclR helix-turn-helix domain. | 0.445 |
| ADU46916.1 | ADU46915.1 | Intca_0367 | Intca_0366 | COGs: COG2132 Putative multicopper oxidase; InterPro IPR017909: IPR011707: IPR011706: IPR002355; KEGG: sli:Slin_6866 bilirubin oxidase; PFAM: multicopper oxidase type 3; multicopper oxidase type 2; SPTR: Bilirubin oxidase; PFAM: Multicopper oxidase. | COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: cai:Caci_4507 acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Acetate/CoA ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme. | 0.435 |
| ADU46916.1 | ADU46918.1 | Intca_0367 | Intca_0369 | COGs: COG2132 Putative multicopper oxidase; InterPro IPR017909: IPR011707: IPR011706: IPR002355; KEGG: sli:Slin_6866 bilirubin oxidase; PFAM: multicopper oxidase type 3; multicopper oxidase type 2; SPTR: Bilirubin oxidase; PFAM: Multicopper oxidase. | Transcriptional regulator, CadC; COGs: COG3710 DNA-binding winged-HTH domains; InterPro IPR001867: IPR000073; KEGG: msm:MSMEG_3856 transcriptional regulator, CadC; PFAM: transcriptional regulator domain-containing protein; alpha/beta hydrolase fold; SPTR: Transcriptional regulator, CadC; PFAM: Transcriptional regulatory protein, C terminal; alpha/beta hydrolase fold. | 0.484 |
| ADU46916.1 | ADU46919.1 | Intca_0367 | Intca_0370 | COGs: COG2132 Putative multicopper oxidase; InterPro IPR017909: IPR011707: IPR011706: IPR002355; KEGG: sli:Slin_6866 bilirubin oxidase; PFAM: multicopper oxidase type 3; multicopper oxidase type 2; SPTR: Bilirubin oxidase; PFAM: Multicopper oxidase. | FAD dependent oxidoreductase; COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR006076: IPR003042; KEGG: sen:SACE_3335 monooxygenase, FAD-binding; PFAM: FAD dependent oxidoreductase; SPTR: Monooxygenase, FAD-binding; PFAM: FAD binding domain. | 0.402 |
| ADU46916.1 | ADU46920.1 | Intca_0367 | Intca_0371 | COGs: COG2132 Putative multicopper oxidase; InterPro IPR017909: IPR011707: IPR011706: IPR002355; KEGG: sli:Slin_6866 bilirubin oxidase; PFAM: multicopper oxidase type 3; multicopper oxidase type 2; SPTR: Bilirubin oxidase; PFAM: Multicopper oxidase. | OsmC family protein; COGs: COG1765 redox protein regulator of disulfide bond formation; InterPro IPR003718; KEGG: ade:Adeh_2254 OsmC-like protein; PFAM: OsmC family protein; SPTR: OsmC-like protein; PFAM: OsmC-like protein. | 0.458 |
| ADU46916.1 | ADU47307.1 | Intca_0367 | Intca_0766 | COGs: COG2132 Putative multicopper oxidase; InterPro IPR017909: IPR011707: IPR011706: IPR002355; KEGG: sli:Slin_6866 bilirubin oxidase; PFAM: multicopper oxidase type 3; multicopper oxidase type 2; SPTR: Bilirubin oxidase; PFAM: Multicopper oxidase. | Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR006121: IPR001757: IPR008250: IPR005834: IPR 006403: IPR006416: IPR018303; KEGG: rha:RHA1_ro11210 copper-exporting ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Putative cation-transporting ATPase; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Heavy-metal-associated doma [...] | 0.562 |
| ADU46916.1 | ADU48527.1 | Intca_0367 | Intca_2016 | COGs: COG2132 Putative multicopper oxidase; InterPro IPR017909: IPR011707: IPR011706: IPR002355; KEGG: sli:Slin_6866 bilirubin oxidase; PFAM: multicopper oxidase type 3; multicopper oxidase type 2; SPTR: Bilirubin oxidase; PFAM: Multicopper oxidase. | KEGG: cfl:Cfla_2099 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.557 |
| ADU46916.1 | ADU49484.1 | Intca_0367 | Intca_2993 | COGs: COG2132 Putative multicopper oxidase; InterPro IPR017909: IPR011707: IPR011706: IPR002355; KEGG: sli:Slin_6866 bilirubin oxidase; PFAM: multicopper oxidase type 3; multicopper oxidase type 2; SPTR: Bilirubin oxidase; PFAM: Multicopper oxidase. | Copper-translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR011017: IPR001757: IPR000695: IPR008250: IPR 005834: IPR007029: IPR006403: IPR006416: IPR018303; KEGG: nca:Noca_2922 copper-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; YHS domain-containing protein; SMART: TRASH domain-containing protein; SPTR: Copper-translocating P-type ATPase; TIGRFAM: copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC [...] | 0.640 |
| ADU46916.1 | argS | Intca_0367 | Intca_0368 | COGs: COG2132 Putative multicopper oxidase; InterPro IPR017909: IPR011707: IPR011706: IPR002355; KEGG: sli:Slin_6866 bilirubin oxidase; PFAM: multicopper oxidase type 3; multicopper oxidase type 2; SPTR: Bilirubin oxidase; PFAM: Multicopper oxidase. | COGs: COG0018 Arginyl-tRNA synthetase; InterProIPR005148: IPR015945: IPR008909: IPR001278: IPR 001412; KEGG: tfu:Tfu_0269 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; arginyl tRNA synthetase domain protein; DALR anticodon binding domain protein; PRIAM: Arginine--tRNA ligase; SPTR: Arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase. | 0.770 |
| ADU46918.1 | ADU46916.1 | Intca_0369 | Intca_0367 | Transcriptional regulator, CadC; COGs: COG3710 DNA-binding winged-HTH domains; InterPro IPR001867: IPR000073; KEGG: msm:MSMEG_3856 transcriptional regulator, CadC; PFAM: transcriptional regulator domain-containing protein; alpha/beta hydrolase fold; SPTR: Transcriptional regulator, CadC; PFAM: Transcriptional regulatory protein, C terminal; alpha/beta hydrolase fold. | COGs: COG2132 Putative multicopper oxidase; InterPro IPR017909: IPR011707: IPR011706: IPR002355; KEGG: sli:Slin_6866 bilirubin oxidase; PFAM: multicopper oxidase type 3; multicopper oxidase type 2; SPTR: Bilirubin oxidase; PFAM: Multicopper oxidase. | 0.484 |
| ADU46918.1 | ADU46919.1 | Intca_0369 | Intca_0370 | Transcriptional regulator, CadC; COGs: COG3710 DNA-binding winged-HTH domains; InterPro IPR001867: IPR000073; KEGG: msm:MSMEG_3856 transcriptional regulator, CadC; PFAM: transcriptional regulator domain-containing protein; alpha/beta hydrolase fold; SPTR: Transcriptional regulator, CadC; PFAM: Transcriptional regulatory protein, C terminal; alpha/beta hydrolase fold. | FAD dependent oxidoreductase; COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR006076: IPR003042; KEGG: sen:SACE_3335 monooxygenase, FAD-binding; PFAM: FAD dependent oxidoreductase; SPTR: Monooxygenase, FAD-binding; PFAM: FAD binding domain. | 0.594 |
| ADU46918.1 | ADU46920.1 | Intca_0369 | Intca_0371 | Transcriptional regulator, CadC; COGs: COG3710 DNA-binding winged-HTH domains; InterPro IPR001867: IPR000073; KEGG: msm:MSMEG_3856 transcriptional regulator, CadC; PFAM: transcriptional regulator domain-containing protein; alpha/beta hydrolase fold; SPTR: Transcriptional regulator, CadC; PFAM: Transcriptional regulatory protein, C terminal; alpha/beta hydrolase fold. | OsmC family protein; COGs: COG1765 redox protein regulator of disulfide bond formation; InterPro IPR003718; KEGG: ade:Adeh_2254 OsmC-like protein; PFAM: OsmC family protein; SPTR: OsmC-like protein; PFAM: OsmC-like protein. | 0.594 |
| ADU46918.1 | argS | Intca_0369 | Intca_0368 | Transcriptional regulator, CadC; COGs: COG3710 DNA-binding winged-HTH domains; InterPro IPR001867: IPR000073; KEGG: msm:MSMEG_3856 transcriptional regulator, CadC; PFAM: transcriptional regulator domain-containing protein; alpha/beta hydrolase fold; SPTR: Transcriptional regulator, CadC; PFAM: Transcriptional regulatory protein, C terminal; alpha/beta hydrolase fold. | COGs: COG0018 Arginyl-tRNA synthetase; InterProIPR005148: IPR015945: IPR008909: IPR001278: IPR 001412; KEGG: tfu:Tfu_0269 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; arginyl tRNA synthetase domain protein; DALR anticodon binding domain protein; PRIAM: Arginine--tRNA ligase; SPTR: Arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase. | 0.499 |
| ADU46919.1 | ADU46916.1 | Intca_0370 | Intca_0367 | FAD dependent oxidoreductase; COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR006076: IPR003042; KEGG: sen:SACE_3335 monooxygenase, FAD-binding; PFAM: FAD dependent oxidoreductase; SPTR: Monooxygenase, FAD-binding; PFAM: FAD binding domain. | COGs: COG2132 Putative multicopper oxidase; InterPro IPR017909: IPR011707: IPR011706: IPR002355; KEGG: sli:Slin_6866 bilirubin oxidase; PFAM: multicopper oxidase type 3; multicopper oxidase type 2; SPTR: Bilirubin oxidase; PFAM: Multicopper oxidase. | 0.402 |