STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ADU46927.1COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873: IPR020845; KEGG: nca:Noca_4296 cyclohexanecarboxylate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme; TIGRFAM: cyclohexanecarboxylate-CoA ligase. (541 aa)    
Predicted Functional Partners:
ADU46929.1
COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092: IPR006091: IPR006090; KEGG: nca:Noca_4298 acyl-CoA dehydrogenase domain-containing protein; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: Acyl-CoA dehydrogenase domain protein; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain; TIGRFAM: cyclohexanecarboxyl-CoA dehydrogenase.
  
 
 0.961
ADU46926.1
Beta-ketoadipyl CoA thiolase; COGs: COG0183 Acetyl-CoA acetyltransferase; InterProIPR020616: IPR020617: IPR002155: IPR020615: IPR 020610: IPR001412: IPR020613: IPR012793; KEGG: nml:Namu_0875 beta-ketoadipyl CoA thiolase; PFAM: Thiolase-like; SPTR: Beta-ketoadipyl CoA thiolase; TIGRFAM: beta-ketoadipyl CoA thiolase; acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; beta-ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.807
ADU46925.1
COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753: IPR018376; KEGG: nml:Namu_0873 enoyl-CoA hydratase/isomerase; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: Enoyl-CoA hydratase/isomerase; PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.800
ADU46928.1
COGs: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; InterPro IPR002198: IPR020904: IPR002347; KEGG: nml:Namu_0877 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase.
  
 
 0.788
ADU46924.1
COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092: IPR006091: IPR006090: IPR006089; KEGG: nca:Noca_4293 acyl-CoA dehydrogenase domain-containing protein; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: Acyl-CoA dehydrogenase; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain.
  
  
 0.648
ADU47928.1
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: nml:Namu_4653 hypothetical protein; PFAM: AMP-dependent synthetase and ligase; SPTR: Putative uncharacterized protein; PFAM: AMP-binding enzyme.
  
     0.620
menB
1,4-Dihydroxy-2-naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
 
   
 0.587
acpP
Phosphopantetheine-binding protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 
 0.552
ADU46698.1
Carbamoyl-phosphate synthase L chain ATP-binding protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR005481: IPR005479: IPR005482: IPR000089: IPR 000022: IPR011761: IPR011764: IPR011763; KEGG: kfl:Kfla_3307 carbamoyl-phosphate synthase L chain ATP-binding protein; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; carboxyl transferase; SPTR: Carbamoyl-phosphate synthase L chain ATP-binding protein; PFAM: Car [...]
  
 
 0.520
rplF
LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.481
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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