STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU46966.1PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611: IPR002173; KEGG: art:Arth_2897 ribokinase-like domain-containing protein; PFAM: PfkB domain protein; SPTR: Putative carbohydrate kinase; PFAM: pfkB family carbohydrate kinase. (400 aa)    
Predicted Functional Partners:
ADU46965.1
Carbohydrate ABC transporter substrate-binding protein, CUT1 family; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: kfl:Kfla_5626 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Sugar ABC transporter substrate-binding protein; PFAM: Bacterial extracellular solute-binding protein.
 
    0.920
ADU46967.1
Glycoside hydrolase family 4; COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR001088: IPR019802; KEGG: sgr:SGR_1058 putative 6-phospho-beta-glucosidase; PFAM: glycoside hydrolase family 4; SPTR: Putative 6-phospho-beta-glucosidase; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain.
 
    0.898
ADU46964.1
Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: kfl:Kfla_5625 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Putative uncharacterized protein; PFAM: Binding-protein-dependent transport system inner membrane component.
 
    0.846
ADU46963.1
Carbohydrate ABC transporter membrane protein 2, CUT1 family; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: kfl:Kfla_5624 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Probable ABC transporter permease protein; PFAM: Binding-protein-dependent transport system inner membrane component.
 
    0.829
ADU46750.1
2-keto-myo-inositol dehydratase; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: kfl:Kfla_1685 myo-inosose-2 dehydratase; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Myo-inosose-2 dehydratase; SPTR: Putative myo-inositol catabolism protein; PFAM: Xylose isomerase-like TIM barrel.
 
  
 0.799
hisA
1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; COGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; InterPro IPR010188: IPR006062; KEGG: nda:Ndas_3187 bifunctional HisA/TrpF protein; PFAM: histidine biosynthesis protein; PRIAM: Phosphoribosylanthranilate isomerase; SPTR:1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM: bifunctional HisA/TrpF protein; PFAM: Histidine biosynthesis protein; TIGRFAM: 1-(5-phosphoribosyl)-5-[(5- p [...]
  
  
 0.532
ADU49743.1
PTS system D-fructose-specific IIABC components (F1P-forming), Frc family; COGs: COG1299 Phosphotransferase system fructose-specific IIC component; InterProIPR002178: IPR013011: IPR013014: IPR004715: IPR 003353: IPR006327: IPR003352; KEGG: sco:SCO3196 fructose-specific permease; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; SPTR: Fructose-specific permease; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose-specific, IIB subunnit; PFAM: Phosphotransferase s [...]
  
  
 0.494
ADU47794.1
Hypothetical protein; InterPro IPR017523; KEGG: kse:Ksed_08510 conserved hypothetical protein TIGR03089; SPTR: Putative uncharacterized protein; TIGRFAM: conserved hypothetical protein TIGR03089.
  
  
 0.457
ADU47167.1
Xylose isomerase domain-containing protein TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: fre:Franean1_6143 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Putative uncharacterized protein; PFAM: Xylose isomerase-like TIM barrel.
  
  
 0.446
ADU46968.1
Coagulation factor 5/8 type domain protein; COGs: COG4409 Neuraminidase (sialidase); InterPro IPR000421: IPR017909: IPR012680; KEGG: sgr:SGR_6429 putative neuramidase; PFAM: coagulation factor 5/8 type domain protein; Laminin G sub domain 2; SPTR: Sialidase; PFAM: F5/8 type C domain; BNR/Asp-box repeat; NPCBM-associated, NEW3 domain of alpha-galactosidase.
 
     0.419
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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