STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU46968.1Coagulation factor 5/8 type domain protein; COGs: COG4409 Neuraminidase (sialidase); InterPro IPR000421: IPR017909: IPR012680; KEGG: sgr:SGR_6429 putative neuramidase; PFAM: coagulation factor 5/8 type domain protein; Laminin G sub domain 2; SPTR: Sialidase; PFAM: F5/8 type C domain; BNR/Asp-box repeat; NPCBM-associated, NEW3 domain of alpha-galactosidase. (825 aa)    
Predicted Functional Partners:
ADU49936.1
COGs: COG3345 Alpha-galactosidase; InterPro IPR002252: IPR000111; KEGG: kfl:Kfla_1749 glycoside hydrolase clan GH-D; PFAM: glycoside hydrolase clan GH-D; PRIAM: Alpha-galactosidase; SPTR: Glycoside hydrolase clan GH-D; PFAM: Melibiase.
  
  
  0.911
ADU47475.1
COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220: IPR020625; KEGG: sro:Sros_2475 putative dihydropicolinate synthase family protein; PFAM: dihydrodipicolinate synthetase; SPTR: Dihydrodipicolinate synthetase; PFAM: Dihydrodipicolinate synthetase family; Belongs to the DapA family.
 
   
 0.702
ADU47277.1
Helicase domain protein; COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR014001: IPR001650: IPR014021: IPR006935; KEGG: ske:Sked_31430 DNA/RNA helicase, superfamily II; PFAM: helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicase; helicase domain protein; SPTR: Putative ATP-dependent DNA helicase; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit.
   
    0.676
ADU47827.1
Type III restriction protein res subunit; COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR006935: IPR014001: IPR014021; KEGG: kse:Ksed_10520 DNA/RNA helicase, superfamily II; PFAM: type III restriction protein res subunit; SMART: DEAD-like helicase; SPTR: Putative uncharacterized protein; manually curated; PFAM: Type III restriction enzyme, res subunit.
   
    0.676
nanE
N-acylglucosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
 
   
 0.595
ADU47476.1
ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600: IPR002328; KEGG: bcv:Bcav_3770 ROK family protein; PFAM: ROK family protein; SPTR: ROK family protein; PFAM: ROK family.
 
   
 0.552
ADU48648.1
COGs: COG2939 Carboxypeptidase C (cathepsin A); InterPro IPR001563; KEGG: svi:Svir_32200 carboxypeptidase C (cathepsin A); PFAM: peptidase S10 serine carboxypeptidase; SPTR: Carboxypeptidase C (Cathepsin A); PFAM: Serine carboxypeptidase.
  
 0.552
ADU49570.1
Helicase domain protein; InterPro IPR001650; KEGG: xce:Xcel_2322 helicase domain protein; PFAM: helicase domain protein; SPTR: Helicase domain protein; PFAM: Helicase conserved C-terminal domain.
   
    0.485
ADU47473.1
Oligopeptide/dipeptide ABC transporter, ATPase subunit; COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterProIPR000515: IPR003439: IPR013563: IPR017871: IPR 010066: IPR003593; KEGG: sma:SAV_5609 ABC transporter permease protein; PFAM: ABC transporter related; binding-protein-dependent transport systems inner membrane component; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: Oligopeptide/dipeptide ABC transporter, ATPase subunit; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transpor [...]
 
     0.478
ADU46967.1
Glycoside hydrolase family 4; COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR001088: IPR019802; KEGG: sgr:SGR_1058 putative 6-phospho-beta-glucosidase; PFAM: glycoside hydrolase family 4; SPTR: Putative 6-phospho-beta-glucosidase; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain.
       0.466
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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