Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADU47004.1Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198: IPR020904: IPR002347; KEGG: krh:KRH_14530 putative oxidoreductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Putative oxidoreductase; PFAM: short chain dehydrogenase. (302 aa)    
Predicted Functional Partners:
ADU47003.1
F420-dependent oxidoreductase, G6PDH family; COGs: COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase; InterPro IPR019945; KEGG: mgi:Mflv_3722 putative dehydrogenase protein; SPTR: Putative dehydrogenase protein; TIGRFAM: F420-dependent oxidoreductase, G6PDH family; PFAM: Luciferase-like monooxygenase; TIGRFAM: F420-dependent oxidoreductase, G6PDH family.
 
     0.802
ADU47002.1
Alpha amylase catalytic region; COGs: COG0366 Glycosidase; InterPro IPR006047: IPR006589; KEGG: mgi:Mflv_3723 alpha amylase, catalytic region; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: Alpha amylase, catalytic region; PFAM: Alpha amylase, catalytic domain; TIGRFAM: trehalose synthase.
 
 
   0.617
ADU46988.1
COGs: COG3569 Topoisomerase IB; InterPro IPR001631; KEGG: amd:AMED_4291 DNA topoisomerase IB; SPTR: Putative uncharacterized protein; PFAM: Eukaryotic DNA topoisomerase I, catalytic core.
  
 
   0.561
ADU46997.1
FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR017941: IPR006076; KEGG: nda:Ndas_1353 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; Rieske [2Fe-2S] iron-sulphur domain; SPTR: FAD dependent oxidoreductase; PFAM: Rieske [2Fe-2S] domain; FAD dependent oxidoreductase.
  
 0.539
ADU47001.1
ABC transporter related protein; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003439: IPR017940: IPR003593; KEGG: nca:Noca_2806 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter transmembrane region; ABC transporter.
 
 
  0.486
ADU47005.1
Glutamate--cysteine ligase GCS2; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
  
    0.475
ADU47006.1
Hypothetical protein; KEGG: der:Dere_GG19401 GG19401 gene product from transcript GG19401-RA; SPTR: Putative uncharacterized protein.
       0.473
ADU49522.1
COGs: COG0777 Acetyl-CoA carboxylase beta subunit; InterPro IPR011762: IPR011763: IPR000438: IPR000022; KEGG: nca:Noca_4502 carboxyl transferase; PFAM: carboxyl transferase; SPTR: Carboxyl transferase; PFAM: Carboxyl transferase domain; TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, beta subunit.
  
  
 0.454
ADU48425.1
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR001753: IPR006176: IPR006108; KEGG: tcu:Tcur_1759 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; SPTR: 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
  
 0.408
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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