STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47023.1Endoribonuclease L-PSP; COGs: COG0251 Putative translation initiation inhibitor yjgF family; InterPro IPR006175; KEGG: lxx:Lxx03610 translation initiation inhibitor; PFAM: Endoribonuclease L-PSP; SPTR: Translation initiation inhibitor; PFAM: Endoribonuclease L-PSP. (156 aa)    
Predicted Functional Partners:
ADU47024.1
NUDIX hydrolase; InterPro IPR000086; KEGG: kse:Ksed_25420 NUDIX family protein; PFAM: NUDIX hydrolase; SPTR: NUDIX family protein; PFAM: NUDIX domain.
  
    0.845
ADU47022.1
KEGG: fre:Franean1_0333 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.841
ADU48058.1
COGs: COG0480 Translation elongation factors (GTPase); InterProIPR005225: IPR000795: IPR004161: IPR005517: IPR 000640; KEGG: nca:Noca_4599 elongation factor G; PFAM: elongation factor G domain IV; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein; SPTR: Translation elongation factor EF-G; TIGRFAM: small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small [...]
   
  0.772
fusA
Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...]
   
  0.772
ADU47025.1
COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: kse:Ksed_25410 Zn-dependent hydrolase, glyoxylase; SPTR: Putative hydrolase; PFAM: Metallo-beta-lactamase superfamily.
  
    0.650
rph
RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
 
 0.457
ADU47021.1
KEGG: mxa:MXAN_0913 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Prolyl oligopeptidase family.
       0.431
ADU47014.1
Metallophosphoesterase; COGs: COG1408 phosphohydrolase; InterPro IPR004843; KEGG: kse:Ksed_25470 predicted phosphohydrolase; PFAM: metallophosphoesterase; SPTR: Predicted phosphohydrolase; PFAM: Calcineurin-like phosphoesterase.
 
     0.430
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
  
 0.408
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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