STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47034.1COGs: COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism; InterPro IPR005467: IPR013767: IPR003594: IPR004358; KEGG: sco:SCO1137 two component system histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Putative two component system histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (560 aa)    
Predicted Functional Partners:
ADU47035.1
Response regulator receiver and unknown domain protein; COGs: COG4565 Response regulator of citrate/malate metabolism; InterPro IPR001789; KEGG: sco:SCO1136 two component system response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Putative two component system response regulator; PFAM: IclR helix-turn-helix domain; Response regulator receiver domain.
 
 
 0.974
ADU49872.1
Response regulator receiver and unknown domain protein; COGs: COG4565 Response regulator of citrate/malate metabolism; InterPro IPR001789; KEGG: gob:Gobs_2259 response regulator receiver and unknown domain protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Putative two-component system response regulator; PFAM: Response regulator receiver domain.
 
 
 0.919
ADU47032.1
KEGG: mjl:Mjls_3247 integral membrane protein; SPTR: Putative integral membrane protein; PFAM: Tripartite tricarboxylate transporter TctB family.
 
     0.883
ADU47033.1
COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: art:Arth_1395 hypothetical protein; SPTR: Putative secreted protein; PFAM: Tripartite tricarboxylate transporter family receptor.
 
    0.879
ADU47031.1
Protein of unknown function DUF112 transmembrane; COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: ach:Achl_0594 protein of unknown function DUF112 transmembrane; PFAM: protein of unknown function DUF112 transmembrane; SPTR: Putative integral membrane protein; PFAM: Tripartite tricarboxylate transporter TctA family.
 
     0.795
ADU47030.1
UspA domain-containing protein; InterPro IPR006016: IPR006015; KEGG: aau:AAur_0701 universal stress family domain-containing protein; PFAM: UspA domain-containing protein; SPTR: Putative uncharacterized protein; PFAM: Universal stress protein family.
       0.567
ADU49870.1
COGs: COG1301 Na+/H+-dicarboxylate symporter; InterPro IPR001991; KEGG: sro:Sros_3870 sodium:dicarboxylate symporter; PFAM: sodium:dicarboxylate symporter; SPTR: Putative sodium:dicarboxylate symporter; PFAM: Sodium:dicarboxylate symporter family; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
 
  
 0.502
ADU47036.1
Peptidase S8 and S53 subtilisin kexin sedolisin; COGs: COG1404 Subtilisin-like serine protease; InterPro IPR010259: IPR000209; KEGG: sro:Sros_3301 putative serine protease; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proteinase inhibitor I9 subtilisin propeptide; SPTR: Putative serine protease; PFAM: Peptidase inhibitor I9; Subtilase family.
       0.456
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.