Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU47070.1Transcriptional regulator, BadM/Rrf2 family; COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: cai:Caci_3768 transcriptional regulator, BadM/Rrf2 family; PFAM: protein of unknown function UPF0074; SPTR: Putative uncharacterized protein; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: Transcriptional regulator; TIGRFAM: rrf2 family protein (putative transcriptional regulator). (154 aa)    
Predicted Functional Partners:
ADU48501.1
COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192; KEGG: stp:Strop_3301 aminotransferase, class V; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Putative aminotransferase; PFAM: Aminotransferase class-V.
 
  
 0.720
ADU48897.1
COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR016454: IPR000192; KEGG: cai:Caci_1302 aminotransferase class V; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Putative uncharacterized protein; PFAM: Aminotransferase class-V.
  
  
 0.668
ADU48221.1
SUF system FeS assembly protein, NifU family; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR002871: IPR011341; KEGG: srt:Srot_2325 NifU family SUF system FeS assembly protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: Putative uncharacterized protein; TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family.
  
  
 0.621
ADU47072.1
Sulfate ABC transporter, inner membrane subunit CysW; COGs: COG4208 ABC-type sulfate transport system permease component; InterPro IPR000515: IPR005667: IPR011866; KEGG: rer:RER_37540 sulfate ABC transporter permease protein; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Putative sulfate ABC transporter permease; TIGRFAM: sulfate ABC transporter, inner membrane subunit CysW; sulfate ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: sulfate ABC transporter, permease protein Cys [...]
     
 0.577
cysA
Sulfate ABC transporter, ATPase subunit; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
       0.547
ADU47073.1
Sulfate ABC transporter, inner membrane subunit CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
     
 0.535
ADU47074.1
COGs: COG1613 ABC-type sulfate transport system periplasmic component; InterPro IPR006059: IPR005669; KEGG: rop:ROP_09930 sulfate ABC transporter sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Sulfate ABC transporter sulfate-binding protein; TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: sulfate/thiosulfate-binding protein.
 
  
 0.519
ADU48696.1
phenylacetate-CoA oxygenase/reductase, PaaK subunit; COGs: COG1018 Flavodoxin reductase (ferredoxin-NADPH reductase) family 1; InterProIPR011884: IPR006058: IPR001041: IPR017927: IPR 008333: IPR001433: IPR001709: IPR001221; KEGG: kse:Ksed_09330 phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; SPTR: Phenylacetate-CoA oxygenase/reductase, PaaK subunit; TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Oxidoreductas [...]
  
  
 0.410
ADU49552.1
Oxidoreductase FAD/NAD(P)-binding domain protein; COGs: COG1018 Flavodoxin reductase (ferredoxin-NADPH reductase) family 1; InterProIPR001041: IPR017927: IPR001221: IPR008333: IPR 001433; KEGG: art:Arth_0194 oxidoreductase FAD/NAD(P)-binding subunit; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; ferredoxin; SPTR: Oxidoreductase FAD/NAD(P)-binding domain protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain.
  
  
 0.410
ADU46646.1
COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR000878: IPR006367: IPR006366; KEGG: aau:AAur_3076 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: Uroporphyrin-III C-methyltransferase, C-terminal:Siroheme synthase,N-terminal; TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase, N-terminal domain.
     
 0.401
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.