STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47077.1DEAD/DEAH box helicase domain protein; COGs: COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster; InterPro IPR014021: IPR001650: IPR011545: IPR014001; KEGG: nca:Noca_0370 DEAD/DEAH box helicase domain-containing protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Putative ATP-dependent RNA helicase; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase. (665 aa)    
Predicted Functional Partners:
ADU47078.1
Anti-sigma-factor antagonist; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR002645: IPR003658; KEGG: kfl:Kfla_0571 anti-sigma-factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist.
       0.646
ADU47079.1
Methyltransferase small; COGs: COG2890 Methylase of polypeptide chain release factors; InterPro IPR007848: IPR002052; KEGG: kse:Ksed_25140 methyltransferase family protein; PFAM: methyltransferase small; SPTR: Putative transferase; PFAM: Methyltransferase small domain; TIGRFAM: HemK family putative methylases; Belongs to the methyltransferase superfamily.
       0.598
ADU48801.1
COGs: COG1837 RNA-binding protein (contains KH domain); InterPro IPR020627: IPR004088; KEGG: jde:Jden_0986 KH domain protein; SPTR: Putative uncharacterized protein; Belongs to the UPF0109 family.
  
   
 0.550
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.474
ADU47076.1
Peptidase S8 and S53 subtilisin kexin sedolisin; InterPro IPR010259: IPR000209: IPR003137: IPR007280; KEGG: kfl:Kfla_2384 protease-associated PA domain protein; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proteinase inhibitor I9 subtilisin propeptide; protease-associated PA domain protein; peptidase domain protein; SPTR: Protease-associated PA domain protein; PFAM: PA domain; Peptidase inhibitor I9; Subtilase family.
  
    0.468
ADU50121.1
Single-stranded nucleic acid binding R3H domain-containing protein; COGs: COG1847 RNA-binding protein; InterPro IPR001374; KEGG: kse:Ksed_27000 predicted RNA-binding protein; PFAM: single-stranded nucleic acid binding R3H domain-containing protein; SMART: single-stranded nucleic acid binding R3H domain-containing protein; SPTR: Putative Jag-like protein; PFAM: R3H domain.
      
 0.461
ADU47075.1
Hypothetical protein; KEGG: bfa:Bfae_28470 DNA polymerase III, subunit gamma/tau; SPTR: DNA polymerase III, subunit gamma/tau.
       0.443
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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