STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47078.1Anti-sigma-factor antagonist; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR002645: IPR003658; KEGG: kfl:Kfla_0571 anti-sigma-factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist. (127 aa)    
Predicted Functional Partners:
ADU47303.1
Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001932: IPR007895: IPR010822: IPR003594; KEGG: gob:Gobs_0116 multi-sensor signal transduction histidine kinase; PFAM: Stage II sporulation protein E; MASE1 domain protein; ATP-binding region ATPase domain protein; SMART: protein phosphatase 2C domain protein; SPTR: Multi-sensor signal transduction histidine kinase; PFAM: Stage II sporulation protein E (SpoIIE); MASE1.
 
 
 0.998
ADU49280.1
ABC transporter related protein; COGs: COG1127 ABC-type transport system involved in resistance to organic solvents ATPase component; InterPro IPR003593: IPR003439: IPR017871; KEGG: nca:Noca_0700 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Putative ABC transporter ATP-binding protein; PFAM: ABC transporter.
   
   0.814
ADU47880.1
Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR018486: IPR010822: IPR001932; KEGG: nca:Noca_3481 stage II sporulation E family protein; PFAM: Stage II sporulation protein E; SMART: protein phosphatase 2C domain protein; SPTR: Putative integral membrane protein; PFAM: Stage II sporulation protein E (SpoIIE).
 
 
 0.795
ADU47008.1
RNA polymerase, sigma 28 subunit, Sig B/F/G subfamily; COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; InterProIPR007627: IPR007624: IPR007630: IPR000943: IPR 014322: IPR014284; KEGG: nca:Noca_1393 sigma-70 region 4 domain-containing protein; PFAM: sigma-70 region 2 domain protein; sigma-70 region 3 domain protein; sigma-70 region 4 domain protein; SPTR: Sigma-70 region 4 domain protein; TIGRFAM: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; TIGRFA [...]
 
 
 0.783
ADU47079.1
Methyltransferase small; COGs: COG2890 Methylase of polypeptide chain release factors; InterPro IPR007848: IPR002052; KEGG: kse:Ksed_25140 methyltransferase family protein; PFAM: methyltransferase small; SPTR: Putative transferase; PFAM: Methyltransferase small domain; TIGRFAM: HemK family putative methylases; Belongs to the methyltransferase superfamily.
       0.749
ADU49393.1
ATP-binding region ATPase domain protein; InterPro IPR003018: IPR003594: IPR018247; KEGG: cai:Caci_4163 putative PAS/PAC sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; SPTR: PAS/PAC sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
 
 0.738
ADU47077.1
DEAD/DEAH box helicase domain protein; COGs: COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster; InterPro IPR014021: IPR001650: IPR011545: IPR014001; KEGG: nca:Noca_0370 DEAD/DEAH box helicase domain-containing protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Putative ATP-dependent RNA helicase; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase.
       0.646
ADU49784.1
Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.
   
  
 0.558
ADU47353.1
COGs: COG2049 Allophanate hydrolase subunit 1; InterPro IPR003833: IPR010016; KEGG: svi:Svir_06200 conserved hypothetical protein TIGR00370; PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; SPTR: Putative uncharacterized protein; PFAM: Allophanate hydrolase subunit 1; TIGRFAM: conserved hypothetical protein TIGR00370.
   
    0.512
ADU47354.1
Urea amidolyase related protein; COGs: COG1984 Allophanate hydrolase subunit 2; InterPro IPR003778; KEGG: kfl:Kfla_6553 UreA amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2; SPTR: Urea amidolyase related protein; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; TIGRFAM: biotin-dependent carboxylase uncharacterized domain.
   
    0.512
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.