STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47099.1LmbE family protein; COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: kse:Ksed_25150 uncharacterized LmbE-like protein; PFAM: LmbE family protein; SPTR: Uncharacterized LmbE-like protein; PFAM: GlcNAc-PI de-N-acetylase. (271 aa)    
Predicted Functional Partners:
mshD
Mycothiol biosynthesis acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
  
   
 0.662
ADU47878.1
KEGG: jde:Jden_0944 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: DSBA-like thioredoxin domain.
  
    0.617
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
     0.555
ADU47100.1
Sterol-binding domain protein; InterPro IPR003033; KEGG: saq:Sare_0143 sterol-binding domain-containing protein; PFAM: Sterol-binding domain protein; SPTR: Sterol-binding domain-containing protein; PFAM: SCP-2 sterol transfer family.
       0.523
mshA
UDP-N-acetylglucosamine; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
 
  
 0.495
mshC
cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
 
  
 0.470
ADU48264.1
KEGG: kra:Krad_1834 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3090); TIGRFAM: conserved hypothetical protein.
  
     0.420
ADU47097.1
Extradiol ring-cleavage dioxygenase class III protein subunit B; COGs: COG3384 conserved hypothetical protein; InterPro IPR004183: IPR014436; KEGG: art:Arth_0218 extradiol ring-cleavage dioxygenase III subunit B; PFAM: Extradiol ring-cleavage dioxygenase class III protein subunit B; SPTR: Putative uncharacterized protein; PFAM: Catalytic LigB subunit of aromatic ring-opening dioxygenase.
 
     0.412
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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