Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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ADU47108.1Peptidase M28; COGs: COG3227 Zinc metalloprotease (elastase); InterPro IPR011096: IPR013856: IPR001570: IPR007484; KEGG: sro:Sros_3786 zinc metalloprotease (elastase)-like protein; PFAM: peptidase M28; peptidase M4 thermolysin; Propeptide peptidase M4 and M36; Peptidase M4 thermolysin; SPTR: Zinc metalloprotease (Elastase)-like protein; manually curated; PFAM: Fungalysin/Thermolysin Propeptide Motif; Thermolysin metallopeptidase, alpha-helical domain; Peptidase family M28; Peptidase propeptide and YPEB domain; Thermolysin metallopeptidase, catalytic domain. (1136 aa)    
Predicted Functional Partners:
ADU47107.1
Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: sro:Sros_3515 LysR family regulatory protein; PFAM: regulatory protein LysR; LysR substrate-binding; SPTR: LysR family regulatory protein; manually curated; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family.
 
   
 0.665
ADU49418.1
M6 family metalloprotease domain protein; COGs: COG4412 conserved hypothetical protein; InterPro IPR008757: IPR017683; KEGG: tbi:Tbis_2142 M6 family metalloprotease domain-containing protein; PFAM: peptidase M6 immune inhibitor A; SPTR: Putative secreted protease; TIGRFAM: M6 family metalloprotease domain protein; PFAM: Immune inhibitor A peptidase M6; TIGRFAM: M6 family metalloprotease domain.
  
   
 0.633
ADU50007.1
Putative transcriptional regulator, PucR family; COGs: COG2508 Regulator of polyketide synthase expression; KEGG: sen:SACE_5329 putative transcriptional regulator; SPTR: Putative transcriptional regulator.
  
     0.613
ADU48912.1
InterPro IPR000209; KEGG: kfl:Kfla_5233 peptidase S8/S53 subtilisin kexin sedolisin; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; SPTR: Putative subtilisin-like protease; PFAM: Subtilase family; Belongs to the peptidase S8 family.
  
  
 0.594
ADU47106.1
Dimethylargininase; COGs: COG1834 N-Dimethylarginine dimethylaminohydrolase; InterPro IPR003198; KEGG: kfl:Kfla_3423 dimethylargininase; PFAM: amidinotransferase; PRIAM: Dimethylargininase; SPTR: Dimethylarginine dimethylaminohydrolase; PFAM: Amidinotransferase.
       0.521
ADU46985.1
KEGG: amd:AMED_6555 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.505
ADU50019.1
KEGG: saq:Sare_1132 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.505
ADU47446.1
Hypothetical protein; InterPro IPR018114; KEGG: sro:Sros_2627 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.488
ADU46984.1
KEGG: sro:Sros_2455 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.485
ADU49348.1
YD repeat protein; InterPro IPR003587: IPR006141: IPR006530; KEGG: stp:Strop_1054 YD repeat-containing protein; SMART: Hedgehog/intein hint domain protein; SPTR: YD repeat protein; TIGRFAM: YD repeat protein; PFAM: Protein of unknown function (DUF1557); TIGRFAM: RHS repeat-associated core domain.
  
   
 0.474
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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