STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADU47108.1Peptidase M28; COGs: COG3227 Zinc metalloprotease (elastase); InterPro IPR011096: IPR013856: IPR001570: IPR007484; KEGG: sro:Sros_3786 zinc metalloprotease (elastase)-like protein; PFAM: peptidase M28; peptidase M4 thermolysin; Propeptide peptidase M4 and M36; Peptidase M4 thermolysin; SPTR: Zinc metalloprotease (Elastase)-like protein; manually curated; PFAM: Fungalysin/Thermolysin Propeptide Motif; Thermolysin metallopeptidase, alpha-helical domain; Peptidase family M28; Peptidase propeptide and YPEB domain; Thermolysin metallopeptidase, catalytic domain. (1136 aa)    
Predicted Functional Partners:
ADU47107.1
Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: sro:Sros_3515 LysR family regulatory protein; PFAM: regulatory protein LysR; LysR substrate-binding; SPTR: LysR family regulatory protein; manually curated; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family.
 
   
 0.667
ADU49418.1
M6 family metalloprotease domain protein; COGs: COG4412 conserved hypothetical protein; InterPro IPR008757: IPR017683; KEGG: tbi:Tbis_2142 M6 family metalloprotease domain-containing protein; PFAM: peptidase M6 immune inhibitor A; SPTR: Putative secreted protease; TIGRFAM: M6 family metalloprotease domain protein; PFAM: Immune inhibitor A peptidase M6; TIGRFAM: M6 family metalloprotease domain.
  
   
 0.633
ADU48912.1
InterPro IPR000209; KEGG: kfl:Kfla_5233 peptidase S8/S53 subtilisin kexin sedolisin; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; SPTR: Putative subtilisin-like protease; PFAM: Subtilase family; Belongs to the peptidase S8 family.
  
  
 0.613
ADU50007.1
Putative transcriptional regulator, PucR family; COGs: COG2508 Regulator of polyketide synthase expression; KEGG: sen:SACE_5329 putative transcriptional regulator; SPTR: Putative transcriptional regulator.
  
     0.613
ADU47012.1
Phospholipase D/Transphosphatidylase; COGs: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: amd:AMED_4111 hypothetical protein; PFAM: phospholipase D/Transphosphatidylase; SPTR: Phospholipase D; PFAM: Phospholipase D Active site motif.
    
 0.595
ADU49568.1
Phospholipase D/Transphosphatidylase; COGs: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: ske:Sked_03300 hypothetical protein; SMART: phospholipase D/Transphosphatidylase; SPTR: Phospholipase D/Transphosphatidylase.
    
 0.595
ADU49569.1
Protein of unknown function DUF1998; InterPro IPR018973; KEGG: xce:Xcel_2321 hypothetical protein; PFAM: Protein of unknown function DUF1998; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF1998).
    
 0.595
ADU48268.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.574
ADU47094.1
AAA ATPase central domain protein; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003959: IPR003593: IPR000641; KEGG: kfl:Kfla_5971 AAA ATPase central domain protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase central domain protein; PFAM: ATPase family associated with various cellular activities (AAA).
    
 0.556
ADU49567.1
AAA ATPase central domain protein; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003593: IPR003959; KEGG: stp:Strop_1939 ATPase central domain-containing protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase, central domain protein; PFAM: ATPase family associated with various cellular activities (AAA).
    
 0.556
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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