STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU47123.1H(+)-transporting two-sector ATPase; COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: tcu:Tcur_1710 H(+)-transporting two-sector ATPase; PFAM: cation transporter; PRIAM: H(+)-transporting two-sector ATPase; SPTR: H(+)-transporting two-sector ATPase; PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family. (465 aa)    
Predicted Functional Partners:
ADU47124.1
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148: IPR006037; KEGG: sen:SACE_2151 potassium uptake protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: Potassium uptake protein; PFAM: TrkA-N domain; TrkA-C domain.
 
 
 0.989
ADU47190.1
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148: IPR006037; KEGG: bfa:Bfae_24350 K+ transport system, NAD-binding component; PFAM: TrkA-N domain protein; SPTR: Potassium uptake protein; PFAM: TrkA-N domain; TrkA-C domain.
 
 
 0.957
ADU48442.1
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR006036: IPR003148: IPR006037; KEGG: ske:Sked_16160 K+ transport system, NAD-binding component; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: Putative potassium uptake protein; PFAM: TrkA-N domain; TrkA-C domain.
  
 
 0.818
ADU48441.1
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR006036: IPR003148: IPR006037; KEGG: kfl:Kfla_3761 TrkA-N domain protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: Potassium uptake protein; manually curated; PFAM: TrkA-N domain; TrkA-C domain.
  
 
 0.803
ADU48130.1
Fmu (Sun) domain protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR006027: IPR001678; KEGG: cfl:Cfla_1856 Fmu (Sun) domain protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; SPTR: Putative RNA-binding Sun protein; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.589
ADU47122.1
Transcriptional regulator, ArsR family; COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: mjl:Mjls_3530 ArsR family transcriptional regulator; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: Transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family.
       0.572
ADU47121.1
InterPro IPR013538; KEGG: mjl:Mjls_3529 hypothetical protein; PFAM: Activator of Hsp90 ATPase 1 family protein; SPTR: Activator of Hsp90 ATPase 1 family protein; PFAM: Activator of Hsp90 ATPase homolog 1-like protein.
       0.511
katG
Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
       0.479
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.467
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.