Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADU47139.1COGs: COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4); InterPro IPR000667; KEGG: kra:Krad_0527 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13 D-Ala-D-Ala carboxypeptidase C; SPTR: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: D-alanyl-D-alanine carboxypeptidase; D-Ala-D-Ala carboxypeptidase 3 (S13) family; TIGRFAM: D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family. (506 aa)    
Predicted Functional Partners:
ADU46626.1
Cell elongation-specific peptidoglycan D,D-transpeptidase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR001460; KEGG: kse:Ksed_00200 cell division protein FtsI/penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: PbpA; PFAM: Penicillin binding protein transpeptidase domain.
     
 0.951
ADU47718.1
COGs: COG1686 D-alanyl-D-alanine carboxypeptidase; InterPro IPR001967: IPR003342: IPR018493: IPR018044; KEGG: tbi:Tbis_0672 peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; glycosyl transferase family 39; SPTR: Probable penicillin-binding protein dacb1 (D-alanyl-d-alaninecarboxypeptidase) (Dd-peptidase) (Dd-carboxypeptidase); PFAM: D-alanyl-D-alanine carboxypeptidase; Dolichyl-phosphate-mannose-protein mannosyltransferase; Belongs to the peptidase S11 family.
     
 0.947
ADU48714.1
Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311: IPR001460; KEGG: tbi:Tbis_1685 penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative penicillin-binding protein; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2.
     
 0.910
ppa
Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
       0.645
ADU47141.1
COGs: COG5282 conserved hypothetical protein; InterPro IPR018766; KEGG: kra:Krad_0528 hypothetical protein; PFAM: Protein of unknown function DUF2342; SPTR: Putative uncharacterized protein; TIGRFAM: conserved hypothetical protein; PFAM: Uncharacterised conserved protein (DUF2342); TIGRFAM: putative hydrolase; uncharacterized protein, coenzyme F420 biosynthesis associated.
  
  
 0.636
ADU49270.1
KEGG: kfl:Kfla_6144 hypothetical protein; SPTR: Putative uncharacterized protein.
   
 
 0.605
ADU49271.1
KEGG: sma:SAV_5893 hypothetical protein; SPTR: Putative uncharacterized protein.
   
 
 0.605
ADU49895.1
Ankyrin; InterPro IPR002110: IPR020683; KEGG: nda:Ndas_2707 ankyrin; PFAM: Ankyrin; SMART: Ankyrin; SPTR: Ankyrin; PFAM: Ankyrin repeat.
   
 
 0.605
ADU47016.1
Peptidoglycan glycosyltransferase; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264: IPR001460; KEGG: kse:Ksed_25450 membrane carboxypeptidase (penicillin-binding protein); PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative transpeptidase; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase.
  
   
 0.598
ADU50092.1
Peptidoglycan glycosyltransferase; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264: IPR001460; KEGG: kra:Krad_4341 glycosyl transferase family 51; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative secreted penicillin-binding protein; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase.
  
   
 0.586
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (12%) [HD]