STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47149.1KEGG: ske:Sked_32050 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3180). (167 aa)    
Predicted Functional Partners:
ADU47148.1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
       0.870
ADU47147.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
       0.837
ADU47150.1
KEGG: stp:Strop_0985 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
folE
COGs: COG0302 GTP cyclohydrolase I; InterPro IPR020602: IPR001474: IPR018234; KEGG: ske:Sked_32080 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I.
  
    0.760
ftsH
Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
       0.754
ADU47517.1
KEGG: kse:Ksed_07270 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.727
ADU49002.1
SAF domain protein; InterPro IPR013974; KEGG: cfl:Cfla_2320 hypothetical protein; PFAM: SAF domain protein; SPTR: Putative uncharacterized protein.
  
     0.672
ADU48622.1
KEGG: ske:Sked_14030 hypothetical protein; SPTR: DNA primase.
  
     0.614
ADU47422.1
KEGG: kse:Ksed_23860 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.604
ADU49423.1
KEGG: cfl:Cfla_0662 putative lipoprotein; SPTR: Putative lipoprotein.
  
     0.577
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.