| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADU47147.1 | ADU47148.1 | Intca_0602 | Intca_0603 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
| ADU47147.1 | ADU47149.1 | Intca_0602 | Intca_0604 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | KEGG: ske:Sked_32050 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3180). | 0.837 |
| ADU47147.1 | ADU47150.1 | Intca_0602 | Intca_0605 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | KEGG: stp:Strop_0985 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.773 |
| ADU47147.1 | folE | Intca_0602 | Intca_0601 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | COGs: COG0302 GTP cyclohydrolase I; InterPro IPR020602: IPR001474: IPR018234; KEGG: ske:Sked_32080 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I. | 0.994 |
| ADU47147.1 | ftsH | Intca_0602 | Intca_0600 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.831 |
| ADU47148.1 | ADU47147.1 | Intca_0603 | Intca_0602 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
| ADU47148.1 | ADU47149.1 | Intca_0603 | Intca_0604 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | KEGG: ske:Sked_32050 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3180). | 0.870 |
| ADU47148.1 | ADU47150.1 | Intca_0603 | Intca_0605 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | KEGG: stp:Strop_0985 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.773 |
| ADU47148.1 | folE | Intca_0603 | Intca_0601 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | COGs: COG0302 GTP cyclohydrolase I; InterPro IPR020602: IPR001474: IPR018234; KEGG: ske:Sked_32080 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I. | 0.999 |
| ADU47148.1 | ftsH | Intca_0603 | Intca_0600 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.913 |
| ADU47149.1 | ADU47147.1 | Intca_0604 | Intca_0602 | KEGG: ske:Sked_32050 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3180). | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.837 |
| ADU47149.1 | ADU47148.1 | Intca_0604 | Intca_0603 | KEGG: ske:Sked_32050 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3180). | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.870 |
| ADU47149.1 | ADU47150.1 | Intca_0604 | Intca_0605 | KEGG: ske:Sked_32050 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3180). | KEGG: stp:Strop_0985 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.773 |
| ADU47149.1 | folE | Intca_0604 | Intca_0601 | KEGG: ske:Sked_32050 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3180). | COGs: COG0302 GTP cyclohydrolase I; InterPro IPR020602: IPR001474: IPR018234; KEGG: ske:Sked_32080 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I. | 0.760 |
| ADU47149.1 | ftsH | Intca_0604 | Intca_0600 | KEGG: ske:Sked_32050 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3180). | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.754 |
| ADU47150.1 | ADU47147.1 | Intca_0605 | Intca_0602 | KEGG: stp:Strop_0985 hypothetical protein; SPTR: Putative uncharacterized protein. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.773 |
| ADU47150.1 | ADU47148.1 | Intca_0605 | Intca_0603 | KEGG: stp:Strop_0985 hypothetical protein; SPTR: Putative uncharacterized protein. | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.773 |
| ADU47150.1 | ADU47149.1 | Intca_0605 | Intca_0604 | KEGG: stp:Strop_0985 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: ske:Sked_32050 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3180). | 0.773 |
| ADU47150.1 | folE | Intca_0605 | Intca_0601 | KEGG: stp:Strop_0985 hypothetical protein; SPTR: Putative uncharacterized protein. | COGs: COG0302 GTP cyclohydrolase I; InterPro IPR020602: IPR001474: IPR018234; KEGG: ske:Sked_32080 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I. | 0.658 |
| ADU47150.1 | ftsH | Intca_0605 | Intca_0600 | KEGG: stp:Strop_0985 hypothetical protein; SPTR: Putative uncharacterized protein. | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.658 |