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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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ADU47154.1Protein of unknown function DUF185; COGs: COG1565 conserved hypothetical protein; InterPro IPR003788; KEGG: sgr:SGR_4103 hypothetical protein; PFAM: protein of unknown function DUF185; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized ACR, COG1565. (325 aa)    
Predicted Functional Partners:
nuoD
NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
 
 
 0.887
nuoI-2
4Fe-4S ferredoxin iron-sulfur binding domain protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
 
  
 0.835
ADU47153.1
Copper resistance protein CopC; COGs: COG2372 conserved hypothetical protein homolog of Cu resistance protein CopC; InterPro IPR007348; KEGG: aau:AAur_0407 copper resistance protein CopC; PFAM: copper resistance protein CopC; SPTR: Putative copper resistance protein, CopC family; PFAM: Copper resistance protein CopC.
       0.781
ADU47256.1
COGs: COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit; InterPro IPR001268; KEGG: tcu:Tcur_4386 NADH (or F420H2) dehydrogenase, subunit C; PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; SPTR: Putative NADH dehydrogenase; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit.
 
 
 0.746
ADU47155.1
Putative oxidoreductase/dehydrogenase, Rossmann-like domain; COGs: COG5495 conserved hypothetical protein; InterPro IPR019665: IPR018931; KEGG: tcu:Tcur_4488 NADP oxidoreductase coenzyme F420-dependent; PFAM: Putative oxidoreductase/dehydrogenase, Rossmann-like domain; Domain of unknown function DUF2520; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF2520); Rossmann-like domain.
       0.656
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
       0.656
ADU49093.1
KEGG: tcu:Tcur_1191 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.619
ADU47151.1
KEGG: mul:MUL_0582 hypothetical protein; SPTR: Conserved protein.
       0.608
ADU47254.1
NADH dehydrogenase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.
 
  
  0.590
nuoH-2
NADH dehydrogenase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.
  
  
  0.580
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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