STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (315 aa)    
Predicted Functional Partners:
panD
L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
 
 0.999
panB
Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
  
 0.997
ADU47155.1
Putative oxidoreductase/dehydrogenase, Rossmann-like domain; COGs: COG5495 conserved hypothetical protein; InterPro IPR019665: IPR018931; KEGG: tcu:Tcur_4488 NADP oxidoreductase coenzyme F420-dependent; PFAM: Putative oxidoreductase/dehydrogenase, Rossmann-like domain; Domain of unknown function DUF2520; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF2520); Rossmann-like domain.
   
 0.987
ADU46948.1
Ketopantoate reductase ApbA/PanE domain protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.933
coaA
COGs: COG1072 Panthothenate kinase; InterPro IPR004566; KEGG: kra:Krad_0723 pantothenate kinase; SPTR: Pantothenate kinase; TIGRFAM: pantothenate kinase; PFAM: Phosphoribulokinase / Uridine kinase family; TIGRFAM: pantothenate kinase, bacterial type.
     
 0.915
cmk
COGs: COG0283 Cytidylate kinase; InterPro IPR003136: IPR011994; KEGG: ske:Sked_19860 cytidylate kinase; PFAM: cytidylate kinase region; SPTR: Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
      0.910
ADU48124.1
COGs: COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; InterPro IPR003382: IPR007085: IPR005252; KEGG: kse:Ksed_12740 phosphopantothenate-cysteine ligase/phosphopantothenoylcysteine decarboxylase; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; flavoprotein; PRIAM: Phosphopantothenate--cysteine ligase; SPTR: Phosphopantothenoylcysteine synthase/decarboxylase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA / pantothenate metabolism flavoprotein; Flavoprotein; TIGRFAM: phosphopantothenoylcysteine decarboxylase [...]
 
  
 0.902
ADU48272.1
COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: fal:FRAAL1423 hypothetical protein; PFAM: aminotransferase class-III; SPTR: Aminotransferase class-III; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.902
ADU49369.1
COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814: IPR004632; KEGG: nml:Namu_4960 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; SPTR: 4-aminobutyrate aminotransferase; TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.902
ADU49819.1
Amidase, hydantoinase/carbamoylase family; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010158: IPR002933; KEGG: sro:Sros_1779 allantoate amidohydrolase; PFAM: peptidase M20; SPTR: Putative amino acid hydrolase; TIGRFAM: amidase, hydantoinase/carbamoylase family; PFAM: Peptidase family M20/M25/M40; TIGRFAM: amidase, hydantoinase/carbamoylase family.
     
 0.902
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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