STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47166.1COGs: COG0248 Exopolyphosphatase; InterPro IPR003695; KEGG: tcu:Tcur_2012 Ppx/GppA phosphatase; PFAM: Ppx/GppA phosphatase; SPTR: Putative DNA-binding protein; PFAM: Ppx/GppA phosphatase family. (310 aa)    
Predicted Functional Partners:
ADU47460.1
COGs: COG0248 Exopolyphosphatase; InterPro IPR003695; KEGG: ske:Sked_07880 Ppx/GppA phosphatase; PFAM: Ppx/GppA phosphatase; SPTR: Putative exopolyphosphatase; PFAM: Ppx/GppA phosphatase family.
  
  
0.949
ADU48362.1
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.919
ADU49943.1
RelA/SpoT domain protein; COGs: COG2357 conserved hypothetical protein; InterPro IPR007685; KEGG: nca:Noca_4620 RelA/SpoT domain-containing protein; PFAM: RelA/SpoT domain protein; SPTR: RelA/SpoT domain protein; PFAM: Region found in RelA / SpoT proteins.
     
  0.900
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
 
  
 0.880
ADU47167.1
Xylose isomerase domain-containing protein TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: fre:Franean1_6143 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: Putative uncharacterized protein; PFAM: Xylose isomerase-like TIM barrel.
       0.723
ADU47165.1
ABC-2 type transporter; COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR000412: IPR013525; KEGG: nca:Noca_0479 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: Putative ABC transporter permease protein; PFAM: ABC-2 type transporter; TIGRFAM: ABC transporter efflux protein, DrrB family.
       0.673
ADU47164.1
ABC transporter related protein; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593: IPR003439; KEGG: kse:Ksed_22040 ABC-type multidrug transport system, ATPase component; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC-type multidrug transport system, ATPase component; PFAM: ABC transporter.
       0.629
ADU46986.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 005561: IPR013656: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: ami:Amir_3954 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; PAS fold domain protein; ANTAR domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Multi [...]
     
 0.490
ADU48548.1
Polyphosphate glucokinase; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: kse:Ksed_12150 polyphosphate glucokinase; PFAM: ROK family protein; SPTR: Polyphosphate glucokinase/transcriptional regulator; PFAM: ROK family.
     
 0.481
ADU48370.1
Protein of unknown function DUF28; COGs: COG0217 conserved hypothetical protein; InterPro IPR002876; KEGG: sna:Snas_2629 hypothetical protein; PFAM: protein of unknown function DUF28; SPTR: UPF0082 protein JNB_02440; PFAM: Domain of unknown function DUF28; TIGRFAM: DNA-binding regulatory protein, YebC/PmpR family.
     
 0.473
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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