STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47172.1DNA polymerase LigD, polymerase domain protein; COGs: COG3285 eukaryotic-type DNA primase; InterPro IPR002755: IPR014145; KEGG: nca:Noca_1237 ATP dependent DNA ligase; PFAM: DNA primase small subunit; SPTR: DNA ligase; TIGRFAM: DNA polymerase LigD, polymerase domain protein; TIGRFAM: DNA polymerase LigD, polymerase domain. (303 aa)    
Predicted Functional Partners:
ADU47171.1
DNA polymerase LigD, ligase domain protein; COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR012310: IPR014146: IPR016059; KEGG: cfl:Cfla_1903 DNA polymerase LigD, ligase domain protein; PFAM: ATP dependent DNA ligase; SPTR: DNA ligase; TIGRFAM: DNA polymerase LigD, ligase domain protein; PFAM: ATP dependent DNA ligase domain; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA polymerase LigD, ligase domain.
  
 0.999
ku
DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.961
ADU50001.1
COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR012310: IPR012309; KEGG: nml:Namu_0826 ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: DNA ligase; PFAM: ATP dependent DNA ligase domain; ATP dependent DNA ligase C terminal region.
   
 0.832
ADU49698.1
COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR012310: IPR000977: IPR012309; KEGG: nca:Noca_2845 ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; PRIAM: DNA ligase (ATP); SPTR: Probable DNA ligase; TIGRFAM: DNA ligase I, ATP-dependent Dnl1; PFAM: ATP dependent DNA ligase domain; DNA ligase N terminus; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA ligase I, ATP-dependent (dnl1); Belongs to the ATP-dependent DNA ligase family.
   
 0.744
ADU46988.1
COGs: COG3569 Topoisomerase IB; InterPro IPR001631; KEGG: amd:AMED_4291 DNA topoisomerase IB; SPTR: Putative uncharacterized protein; PFAM: Eukaryotic DNA topoisomerase I, catalytic core.
 
     0.508
ADU47424.1
Protein of unknown function DUF72; COGs: COG1801 conserved hypothetical protein; InterPro IPR002763; KEGG: rha:RHA1_ro02437 hypothetical protein; PFAM: protein of unknown function DUF72; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF72.
 
    0.441
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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