Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADU47183.1CMP/dCMP deaminase zinc-binding protein; COGs: COG0590 Cytosine/adenosine deaminase; InterPro IPR002125; KEGG: tfu:Tfu_1723 hypothetical protein; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: Cytosine/adenine deaminase; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region. (160 aa)    
Predicted Functional Partners:
ADU47184.1
Methyltransferase type 11; COGs: COG2230 Cyclopropane fatty acid synthase and related methyltransferase; InterPro IPR013216; KEGG: sma:SAV_3886 hypothetical protein; PFAM: Methyltransferase type 11; SPTR: Putative uncharacterized protein; PFAM: Cyclopropane-fatty-acyl-phospholipid synthase.
       0.782
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
   
    0.781
ADU47185.1
Protein of unknown function DUF1503; InterPro IPR010872: IPR017517; KEGG: nca:Noca_0119 hypothetical protein; PFAM: protein of unknown function DUF1503; SPTR: Putative uncharacterized protein; PFAM: Mycothiol maleylpyruvate isomerase N-terminal domain; TIGRFAM: uncharacterized Actinobacterial protein TIGR03083.
  
    0.776
hisE
COGs: COG0140 Phosphoribosyl-ATP pyrophosphohydrolase; InterPro IPR008179: IPR021130; KEGG: nda:Ndas_5379 phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase-like; SPTR: Phosphoribosyl-ATP diphosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase.
   
  
 0.750
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
       0.584
ADU47186.1
COGs: COG0506 Proline dehydrogenase; InterPro IPR002872: IPR008219; KEGG: ami:Amir_1081 proline dehydrogenase; PFAM: Proline dehydrogenase; PRIAM: Proline dehydrogenase; SPTR: Proline dehydrogenase; PFAM: Proline dehydrogenase.
       0.558
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.556
ADU48457.1
COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: gob:Gobs_3234 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase family.
  
  
 0.529
ADU47763.1
COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004408: IPR004143: IPR003142; KEGG: tfu:Tfu_2553 biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin protein ligase domain protein; SPTR: Biotin--acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: Biotin protein ligase C terminal domain; Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region.
  
    0.519
ADU46738.1
KEGG: xce:Xcel_3194 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Mycothiol maleylpyruvate isomerase N-terminal domain.
   
  
 0.455
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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