Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (268 aa)    
Predicted Functional Partners:
ADU47186.1
COGs: COG0506 Proline dehydrogenase; InterPro IPR002872: IPR008219; KEGG: ami:Amir_1081 proline dehydrogenase; PFAM: Proline dehydrogenase; PRIAM: Proline dehydrogenase; SPTR: Proline dehydrogenase; PFAM: Proline dehydrogenase.
   
 0.986
ADU47673.1
COGs: COG0506 Proline dehydrogenase; InterPro IPR002872: IPR008219; KEGG: amd:AMED_2662 proline dehydrogenase; PFAM: Proline dehydrogenase; PRIAM: Proline dehydrogenase; SPTR: Putative proline dehydrogenase; PFAM: Proline dehydrogenase.
   
 0.941
ADU49658.1
COGs: COG3938 Proline racemase; InterPro IPR008794; KEGG: sgr:SGR_1624 putative proline racemase; PFAM: proline racemase; PRIAM: Proline racemase; SPTR: Proline racemase; PFAM: Proline racemase; Belongs to the proline racemase family.
    
 0.912
ADU49664.1
COGs: COG3938 Proline racemase; InterPro IPR008794; KEGG: sco:SCO6293 hypothetical protein; PFAM: proline racemase; PRIAM: Proline racemase; SPTR: 4-hydroxyproline epimerase; PFAM: Proline racemase.
    
 0.912
ADU47674.1
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR016160: IPR005931; KEGG: nca:Noca_1220 delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Delta-1-pyrroline-5-carboxylate dehydrogenase 1; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 1.
   
 
 0.906
ADU48993.1
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR005931: IPR015590: IPR016160; KEGG: kse:Ksed_08740 delta-1-pyrroline-5-carboxylate dehydrogenase, group 1; PFAM: Aldehyde Dehydrogenase; SPTR: Delta-1-pyrroline-5-carboxylate dehydrogenase 1; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 1.
   
 
 0.906
ADU47399.1
Proline iminopeptidase; COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR002410: IPR000073: IPR005944; KEGG: kse:Ksed_01230 proline iminopeptidase; PFAM: alpha/beta hydrolase fold; PRIAM: Prolyl aminopeptidase; SPTR: Proline iminopeptidase; TIGRFAM: proline iminopeptidase; manually curated; PFAM: alpha/beta hydrolase fold; TIGRFAM: proline iminopeptidase, Neisseria-type subfamily; Belongs to the peptidase S33 family.
    
  0.903
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 
 0.850
proA
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.830
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.690
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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