STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47201.1Glutaredoxin 2; InterPro IPR008554; KEGG: nca:Noca_0492 glutaredoxin 2; PFAM: glutaredoxin 2; SPTR: Glutaredoxin 2; PFAM: Glutaredoxin-like domain (DUF836). (88 aa)    
Predicted Functional Partners:
ADU47957.1
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 0.921
ADU47200.1
KEGG: kra:Krad_0034 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
ADU47205.1
Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; COGs: COG1587 Uroporphyrinogen-III synthase; InterPro IPR000878: IPR003754: IPR003043; KEGG: kra:Krad_0619 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Putative uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD.
  
  
 0.650
rex
CoA-binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
  
  
 0.621
ADU47212.1
COGs: COG1333 ResB protein required for cytochrome c biosynthesis; KEGG: kra:Krad_0630 ResB family protein; SPTR: Conserved protein, putative c-type cytochrome biogenesis protein; PFAM: ResB-like family.
 
     0.617
ADU48494.1
Menaquinol-cytochrome c reductase cytochrome c1 subunit precursor; InterPro IPR003088: IPR009152: IPR009056; KEGG: kse:Ksed_16190 cytochrome c, mono- and diheme variants family; PFAM: cytochrome c class I; SPTR: Cytochrome C heme-binding subunit; PFAM: Cytochrome c.
  
     0.611
ADU46819.1
COGs: COG3336 membrane protein; InterPro IPR019108; KEGG: kse:Ksed_26540 predicted membrane protein; PFAM: Cytochrome c oxidase caa3-type, assembly factor CtaG-related; SPTR: Putative uncharacterized protein; PFAM: Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG); Copper resistance protein D.
 
     0.586
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
       0.572
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
       0.572
ADU47206.1
Porphobilinogen synthase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: mpa:MAP4005 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; PRIAM: Porphobilinogen synthase; SPTR: Delta-aminolevulinic acid dehydratase; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
       0.557
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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