| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADU47148.1 | ADU47249.1 | Intca_0603 | Intca_0705 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.522 |
| ADU47148.1 | ADU47251.1 | Intca_0603 | Intca_0707 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | RarD protein, DMT superfamily transporter; COGs: COG2962 permease; InterPro IPR000620: IPR004626; KEGG: tpr:Tpau_0604 RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; SPTR: RarD protein, DMT superfamily transporter; TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: EamA-like transporter family; TIGRFAM: rarD protein. | 0.449 |
| ADU47249.1 | ADU47148.1 | Intca_0705 | Intca_0603 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.522 |
| ADU47249.1 | ADU47250.1 | Intca_0705 | Intca_0706 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Drug resistance transporter, EmrB/QacA subfamily; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701: IPR004638; KEGG: nca:Noca_0124 EmrB/QacA family drug resistance transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Drug resistance transporter, EmrB/QacA subfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily. | 0.777 |
| ADU47249.1 | ADU47251.1 | Intca_0705 | Intca_0707 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | RarD protein, DMT superfamily transporter; COGs: COG2962 permease; InterPro IPR000620: IPR004626; KEGG: tpr:Tpau_0604 RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; SPTR: RarD protein, DMT superfamily transporter; TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: EamA-like transporter family; TIGRFAM: rarD protein. | 0.469 |
| ADU47249.1 | ADU47252.1 | Intca_0705 | Intca_0708 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 2-oxoglutarate synthase; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: sen:SACE_3926 2-oxoglutarate ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; PRIAM: 2-oxoglutarate synthase; SPTR: Ferrodoxin oxidoreductase beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | 0.973 |
| ADU47249.1 | ADU47253.1 | Intca_0705 | Intca_0709 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880; KEGG: tfu:Tfu_2674 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: Putative oxidoreductase; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit. | 0.990 |
| ADU47249.1 | ADU49556.1 | Intca_0705 | Intca_3070 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896: IPR011895: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017900; KEGG: mmi:MMAR_3408 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; TIGRFAM [...] | 0.987 |
| ADU47249.1 | ackA | Intca_0705 | Intca_0704 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.999 |
| ADU47249.1 | fumC | Intca_0705 | Intca_0703 | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.907 |
| ADU47250.1 | ADU47249.1 | Intca_0706 | Intca_0705 | Drug resistance transporter, EmrB/QacA subfamily; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701: IPR004638; KEGG: nca:Noca_0124 EmrB/QacA family drug resistance transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Drug resistance transporter, EmrB/QacA subfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily. | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.777 |
| ADU47250.1 | ADU47251.1 | Intca_0706 | Intca_0707 | Drug resistance transporter, EmrB/QacA subfamily; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701: IPR004638; KEGG: nca:Noca_0124 EmrB/QacA family drug resistance transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Drug resistance transporter, EmrB/QacA subfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily. | RarD protein, DMT superfamily transporter; COGs: COG2962 permease; InterPro IPR000620: IPR004626; KEGG: tpr:Tpau_0604 RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; SPTR: RarD protein, DMT superfamily transporter; TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: EamA-like transporter family; TIGRFAM: rarD protein. | 0.563 |
| ADU47250.1 | ADU47252.1 | Intca_0706 | Intca_0708 | Drug resistance transporter, EmrB/QacA subfamily; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701: IPR004638; KEGG: nca:Noca_0124 EmrB/QacA family drug resistance transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Drug resistance transporter, EmrB/QacA subfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily. | 2-oxoglutarate synthase; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: sen:SACE_3926 2-oxoglutarate ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; PRIAM: 2-oxoglutarate synthase; SPTR: Ferrodoxin oxidoreductase beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | 0.470 |
| ADU47250.1 | ADU47253.1 | Intca_0706 | Intca_0709 | Drug resistance transporter, EmrB/QacA subfamily; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701: IPR004638; KEGG: nca:Noca_0124 EmrB/QacA family drug resistance transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Drug resistance transporter, EmrB/QacA subfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily. | Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880; KEGG: tfu:Tfu_2674 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: Putative oxidoreductase; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit. | 0.529 |
| ADU47250.1 | ackA | Intca_0706 | Intca_0704 | Drug resistance transporter, EmrB/QacA subfamily; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701: IPR004638; KEGG: nca:Noca_0124 EmrB/QacA family drug resistance transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Drug resistance transporter, EmrB/QacA subfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.779 |
| ADU47250.1 | fumC | Intca_0706 | Intca_0703 | Drug resistance transporter, EmrB/QacA subfamily; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701: IPR004638; KEGG: nca:Noca_0124 EmrB/QacA family drug resistance transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Drug resistance transporter, EmrB/QacA subfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily. | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.774 |
| ADU47251.1 | ADU47148.1 | Intca_0707 | Intca_0603 | RarD protein, DMT superfamily transporter; COGs: COG2962 permease; InterPro IPR000620: IPR004626; KEGG: tpr:Tpau_0604 RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; SPTR: RarD protein, DMT superfamily transporter; TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: EamA-like transporter family; TIGRFAM: rarD protein. | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.449 |
| ADU47251.1 | ADU47249.1 | Intca_0707 | Intca_0705 | RarD protein, DMT superfamily transporter; COGs: COG2962 permease; InterPro IPR000620: IPR004626; KEGG: tpr:Tpau_0604 RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; SPTR: RarD protein, DMT superfamily transporter; TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: EamA-like transporter family; TIGRFAM: rarD protein. | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.469 |
| ADU47251.1 | ADU47250.1 | Intca_0707 | Intca_0706 | RarD protein, DMT superfamily transporter; COGs: COG2962 permease; InterPro IPR000620: IPR004626; KEGG: tpr:Tpau_0604 RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; SPTR: RarD protein, DMT superfamily transporter; TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: EamA-like transporter family; TIGRFAM: rarD protein. | Drug resistance transporter, EmrB/QacA subfamily; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701: IPR004638; KEGG: nca:Noca_0124 EmrB/QacA family drug resistance transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Drug resistance transporter, EmrB/QacA subfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily. | 0.563 |
| ADU47251.1 | ADU47252.1 | Intca_0707 | Intca_0708 | RarD protein, DMT superfamily transporter; COGs: COG2962 permease; InterPro IPR000620: IPR004626; KEGG: tpr:Tpau_0604 RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; SPTR: RarD protein, DMT superfamily transporter; TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: EamA-like transporter family; TIGRFAM: rarD protein. | 2-oxoglutarate synthase; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: sen:SACE_3926 2-oxoglutarate ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; PRIAM: 2-oxoglutarate synthase; SPTR: Ferrodoxin oxidoreductase beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. | 0.827 |