STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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[Homology]
Score
ADU47251.1RarD protein, DMT superfamily transporter; COGs: COG2962 permease; InterPro IPR000620: IPR004626; KEGG: tpr:Tpau_0604 RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; SPTR: RarD protein, DMT superfamily transporter; TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: EamA-like transporter family; TIGRFAM: rarD protein. (331 aa)    
Predicted Functional Partners:
ADU47253.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880; KEGG: tfu:Tfu_2674 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: Putative oxidoreductase; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit.
       0.840
ADU47252.1
2-oxoglutarate synthase; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: sen:SACE_3926 2-oxoglutarate ferredoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; PRIAM: 2-oxoglutarate synthase; SPTR: Ferrodoxin oxidoreductase beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
       0.820
ADU47250.1
Drug resistance transporter, EmrB/QacA subfamily; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701: IPR004638; KEGG: nca:Noca_0124 EmrB/QacA family drug resistance transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Drug resistance transporter, EmrB/QacA subfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily.
  
    0.572
fumC
Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
       0.490
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
       0.469
ADU47249.1
Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
       0.469
ADU47262.1
Proton-translocating NADH-quinone oxidoreductase, chain M; COGs: COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); InterPro IPR003918: IPR001750: IPR010227; KEGG: sgr:SGR_2917 putative NADH dehydrogenase chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: Putative NADH dehydrogenase I chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M.
 
     0.441
ADU48936.1
Protein of unknown function DUF2550; InterPro IPR019675; KEGG: kra:Krad_1272 hypothetical protein; PFAM: Protein of unknown function DUF2550; SPTR: Putative secreted protein; PFAM: Protein of unknown function (DUF2550).
      
 0.441
ADU47256.1
COGs: COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit; InterPro IPR001268; KEGG: tcu:Tcur_4386 NADH (or F420H2) dehydrogenase, subunit C; PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; SPTR: Putative NADH dehydrogenase; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit.
       0.440
nuoH-2
NADH dehydrogenase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.
       0.433
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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