STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47278.1hydroxymethylglutaryl-CoA lyase; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891; KEGG: kse:Ksed_21580 hydroxymethylglutaryl-CoA lyase; PFAM: pyruvate carboxyltransferase; SPTR: Putative hydroxymethylglutaryl-CoA lyase; PFAM: HMGL-like. (312 aa)    
Predicted Functional Partners:
ADU49556.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896: IPR011895: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017900; KEGG: mmi:MMAR_3408 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; TIGRFAM [...]
  
 
 0.955
ADU47792.1
COGs: COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase alpha subunit; InterPro IPR012792: IPR004163: IPR004165; KEGG: nca:Noca_0330 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase; PRIAM: 3-oxoacid CoA-transferase; SPTR: Putative 3-oxoadipate CoA-transferase subunit A; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: Coenzyme A transferase; TIGRFAM: 3-oxoacid CoA-transferase, A subunit.
  
 
 0.924
ADU47791.1
COGs: COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase beta subunit; InterPro IPR012791: IPR004164: IPR004165; KEGG: nca:Noca_0331 butyryl-CoA:acetate CoA transferase; PFAM: coenzyme A transferase; PRIAM: 3-oxoacid CoA-transferase; SPTR: Butyryl-CoA:acetate CoA transferase; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: Coenzyme A transferase; TIGRFAM: 3-oxoacid CoA-transferase, B subunit.
  
 
 0.923
ADU47253.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880; KEGG: tfu:Tfu_2674 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: Putative oxidoreductase; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit.
  
 
 0.922
ADU47463.1
COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR020616: IPR020617: IPR020613: IPR002155; KEGG: kse:Ksed_07120 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; PRIAM: Acetyl-CoA C-acyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.918
ADU47929.1
COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155: IPR020616: IPR020617; KEGG: pfr:PFREUD_02820 acetyl-CoA C-acetyltransferase; PFAM: Thiolase-like; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: Acetyl-CoA C-acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.918
ADU48401.1
3-ketoacyl-CoA thiolase; COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR020616: IPR020617: IPR002155; KEGG: cwo:Cwoe_0195 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; PRIAM: Acetyl-CoA C-acyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.918
ADU48424.1
COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR020616: IPR020617: IPR002155: IPR020613; KEGG: cai:Caci_6777 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; PRIAM: Acetyl-CoA C-acyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.918
ADU48917.1
COGs: COG0183 Acetyl-CoA acetyltransferase; InterProIPR002155: IPR020615: IPR020610: IPR020613: IPR 020616: IPR020617; KEGG: rer:RER_38940 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.918
ADU48339.1
hydroxymethylglutaryl-CoA lyase; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891; KEGG: fre:Franean1_3719 pyruvate carboxyltransferase; PFAM: pyruvate carboxyltransferase; SPTR: Pyruvate carboxyltransferase; PFAM: HMGL-like.
  
  
 
0.910
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.