STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47293.1Pentapeptide repeat protein; InterPro IPR001646; KEGG: ske:Sked_35000 uncharacterized low-complexity protein; PFAM: pentapeptide repeat protein; SPTR: Uncharacterized low-complexity protein. (218 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.940
ADU47292.1
COGs: COG0372 Citrate synthase; InterPro IPR002020: IPR019810; KEGG: sma:SAV_3859 citrate synthase 2; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: Citrate (Si)-synthase; PFAM: Citrate synthase; Belongs to the citrate synthase family.
       0.545
ADU49876.1
KEGG: scb:SCAB_75571 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.500
ADU48626.1
KEGG: bcv:Bcav_0104 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.435
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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