STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47312.1CHAD domain containing protein; COGs: COG5607 conserved hypothetical protein; InterPro IPR008172: IPR007899; KEGG: kfl:Kfla_0605 CHAD domain containing protein; PFAM: CHAD domain containing protein; adenylate cyclase; SPTR: CHAD domain containing protein; PFAM: CYTH domain; CHAD domain. (517 aa)    
Predicted Functional Partners:
ribA-2
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family.
       0.563
ADU46986.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 005561: IPR013656: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: ami:Amir_3954 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; PAS fold domain protein; ANTAR domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Multi [...]
 
   
 0.540
ADU47313.1
KEGG: ahe:Arch_1155 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Dinitrogenase iron-molybdenum cofactor.
       0.539
ADU46790.1
KEGG: nca:Noca_3909 secreted protein; SPTR: Secreted protein.
 
  
 0.527
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
     
 0.516
ADU47311.1
Molybdopterin oxidoreductase; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterPro IPR006963: IPR006656: IPR006657: IPR006655; KEGG: art:Arth_4046 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
       0.507
ADU50027.1
KEGG: aau:AAur_0122 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.497
ADU47310.1
KEGG: sco:SCO7373 hypothetical protein; SPTR: Putative uncharacterized protein SCO7373.
       0.490
ADU46987.1
Hypothetical protein; KEGG: fre:Franean1_3999 hemerythrin HHE cation binding domain-containing protein; SPTR: Hemerythrin HHE cation binding region.
  
     0.449
glnE
(Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...]
       0.449
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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