STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
cobQAdenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (511 aa)    
Predicted Functional Partners:
ADU47314.1
COGs: COG1010 Precorrin-3B methylase; InterPro IPR000878: IPR006364: IPR006363; KEGG: nda:Ndas_1624 precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: Precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase.
  
 0.998
cobD
Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
 
 0.993
ADU47336.1
cob(I)yrinic acid a,c-diamide adenosyltransferase; COGs: COG2109 ATP:corrinoid adenosyltransferase; InterPro IPR003724; KEGG: svi:Svir_17750 cob(I)yrinic acid a,c-diamide adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; PRIAM: Cob(I)yrinic acid a,c-diamide adenosyltransferase; SPTR: Cob(I)yrinic acid a,c-diamide adenosyltransferase; TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; TIGRFAM: cob(I)alamin adenosyltransferase.
 
  
 0.987
ADU47315.1
precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: tfu:Tfu_0317 precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase CbiC/CobH; PRIAM: Precorrin-8X methylmutase; SPTR: Precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase.
  
 0.981
ADU48522.1
COGs: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; InterPro IPR003203; KEGG: amd:AMED_7046 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; PFAM: cobalbumin biosynthesis protein; SPTR: Adenosylcobinamide kinase; PFAM: Cobinamide kinase / cobinamide phosphate guanyltransferase.
  
 0.976
ADU47333.1
COGs: COG2099 Precorrin-6x reductase; InterPro IPR003723; KEGG: svi:Svir_17710 precorrin-6A reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; PRIAM: Precorrin-6A reductase; SPTR: Precorrin-6x reductase CbiJ/CobK; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK; TIGRFAM: precorrin-6x reductase.
 
  
 0.968
cobB
Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
 0.966
ADU47339.1
COGs: COG2875 Precorrin-4 methylase; InterPro IPR000878: IPR003043; KEGG: tfu:Tfu_0315 precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: Putative methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.957
ADU47331.1
precorrin-6A synthase (deacetylating); COGs: COG2243 Precorrin-2 methylase; InterPro IPR000878: IPR012797; KEGG: mex:Mext_3385 precorrin 6A synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PRIAM: Precorrin-6A synthase (deacetylating); SPTR: Putative uncharacterized protein; TIGRFAM: precorrin-6A synthase (deacetylating); PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-6A synthase (deacetylating).
 
  
 0.951
cobS
Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.949
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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