STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ADU47347.1L-lactate transport; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. (588 aa)    
Predicted Functional Partners:
ADU47345.1
Iron-sulfur cluster binding protein; COGs: COG1139 conserved hypothetical protein containing a ferredoxin-like domain; InterPro IPR003741: IPR004452: IPR017900; KEGG: kse:Ksed_04080 (4Fe-4S) cluster-containing protein; PFAM: protein of unknown function DUF162; SPTR: Putative iron-sulfur protein; TIGRFAM: iron-sulfur cluster binding protein; PFAM: Domain of unknown function (DUF3390); Uncharacterised ACR, YkgG family COG1556; TIGRFAM: iron-sulfur cluster-binding protein.
 
  
 0.919
ADU47344.1
Protein of unknown function DUF162; COGs: COG1556 conserved hypothetical protein; InterPro IPR003741; KEGG: kse:Ksed_04090 hypothetical protein; PFAM: protein of unknown function DUF162; SPTR: Uncharacterized conserved protein; PFAM: Uncharacterised ACR, YkgG family COG1556.
 
  
 0.871
ADU47346.1
Protein of unknown function DUF224 cysteine-rich region domain protein; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017: IPR019758; KEGG: mva:Mvan_2709 hypothetical protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Putative uncharacterized protein; PFAM: Cysteine-rich domain.
 
  
 0.868
ADU47348.1
Transcriptional regulator, GntR family; COGs: COG2186 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: sen:SACE_3508 GntR family transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
 
  
 0.734
ADU49556.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896: IPR011895: IPR002880: IPR019752: IPR 019456: IPR011766: IPR017900; KEGG: mmi:MMAR_3408 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; TIGRFAM [...]
  
  
 0.731
ADU48563.1
(S)-2-hydroxy-acid oxidase; COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR000262: IPR012133: IPR008259; KEGG: sen:SACE_5887 L-lactate dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; PRIAM: (S)-2-hydroxy-acid oxidase; SPTR: L-lactate dehydrogenase; PFAM: FMN-dependent dehydrogenase.
  
  
 0.571
ADU50030.1
COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR012133: IPR000262: IPR008259; KEGG: sen:SACE_6523 lactate 2-monooxygenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: Lactate 2-monooxygenase; PFAM: FMN-dependent dehydrogenase.
  
  
 0.571
ADU47349.1
Cation diffusion facilitator family transporter; COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: mva:Mvan_3225 cation diffusion facilitator family transporter; PFAM: cation efflux protein; SPTR: Cation diffusion facilitator family transporter; TIGRFAM: cation diffusion facilitator family transporter; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
       0.497
ADU49743.1
PTS system D-fructose-specific IIABC components (F1P-forming), Frc family; COGs: COG1299 Phosphotransferase system fructose-specific IIC component; InterProIPR002178: IPR013011: IPR013014: IPR004715: IPR 003353: IPR006327: IPR003352; KEGG: sco:SCO3196 fructose-specific permease; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; SPTR: Fructose-specific permease; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose-specific, IIB subunnit; PFAM: Phosphotransferase s [...]
     
 0.477
ADU47360.1
Protein of unknown function DUF224 cysteine-rich region domain protein; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR017896: IPR004017: IPR012257: IPR017900; KEGG: sen:SACE_6364 glycolate oxidase iron-sulfur subunit; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Glycolate oxidase iron-sulfur subunit; PFAM: Cysteine-rich domain.
 
  
 0.445
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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