STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47349.1Cation diffusion facilitator family transporter; COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: mva:Mvan_3225 cation diffusion facilitator family transporter; PFAM: cation efflux protein; SPTR: Cation diffusion facilitator family transporter; TIGRFAM: cation diffusion facilitator family transporter; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (367 aa)    
Predicted Functional Partners:
ADU47348.1
Transcriptional regulator, GntR family; COGs: COG2186 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: sen:SACE_3508 GntR family transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
       0.730
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
    0.519
ldh
Malate dehydrogenase (NAD); Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
    0.519
ADU47344.1
Protein of unknown function DUF162; COGs: COG1556 conserved hypothetical protein; InterPro IPR003741; KEGG: kse:Ksed_04090 hypothetical protein; PFAM: protein of unknown function DUF162; SPTR: Uncharacterized conserved protein; PFAM: Uncharacterised ACR, YkgG family COG1556.
       0.499
ADU47345.1
Iron-sulfur cluster binding protein; COGs: COG1139 conserved hypothetical protein containing a ferredoxin-like domain; InterPro IPR003741: IPR004452: IPR017900; KEGG: kse:Ksed_04080 (4Fe-4S) cluster-containing protein; PFAM: protein of unknown function DUF162; SPTR: Putative iron-sulfur protein; TIGRFAM: iron-sulfur cluster binding protein; PFAM: Domain of unknown function (DUF3390); Uncharacterised ACR, YkgG family COG1556; TIGRFAM: iron-sulfur cluster-binding protein.
       0.498
ADU47346.1
Protein of unknown function DUF224 cysteine-rich region domain protein; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017: IPR019758; KEGG: mva:Mvan_2709 hypothetical protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Putative uncharacterized protein; PFAM: Cysteine-rich domain.
       0.497
ADU47347.1
L-lactate transport; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
       0.497
ADU46987.1
Hypothetical protein; KEGG: fre:Franean1_3999 hemerythrin HHE cation binding domain-containing protein; SPTR: Hemerythrin HHE cation binding region.
  
     0.442
ADU47307.1
Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR006121: IPR001757: IPR008250: IPR005834: IPR 006403: IPR006416: IPR018303; KEGG: rha:RHA1_ro11210 copper-exporting ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Putative cation-transporting ATPase; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Heavy-metal-associated doma [...]
 
 
 0.432
ADU49907.1
COGs: COG1289 membrane protein; KEGG: dra:DR_2205 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.410
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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