STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47354.1Urea amidolyase related protein; COGs: COG1984 Allophanate hydrolase subunit 2; InterPro IPR003778; KEGG: kfl:Kfla_6553 UreA amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2; SPTR: Urea amidolyase related protein; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; TIGRFAM: biotin-dependent carboxylase uncharacterized domain. (297 aa)    
Predicted Functional Partners:
ADU47353.1
COGs: COG2049 Allophanate hydrolase subunit 1; InterPro IPR003833: IPR010016; KEGG: svi:Svir_06200 conserved hypothetical protein TIGR00370; PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; SPTR: Putative uncharacterized protein; PFAM: Allophanate hydrolase subunit 1; TIGRFAM: conserved hypothetical protein TIGR00370.
 
 0.999
pxpA
LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
  
 0.993
ADU47746.1
Biotin carboxyl carrier protein; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR005481: IPR005479: IPR005482: IPR000089: IPR 001882: IPR011761: IPR011764; KEGG: kse:Ksed_08190 acetyl/propionyl-CoA carboxylase, alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: Putative acyl-CoA carboxylase, alpha subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-te [...]
 
  
 0.930
ADU47818.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
    
 0.832
gatA
aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
    
 0.625
ADU47078.1
Anti-sigma-factor antagonist; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR002645: IPR003658; KEGG: kfl:Kfla_0571 anti-sigma-factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist.
   
    0.512
ADU47355.1
COGs: COG0372 Citrate synthase; InterPro IPR002020: IPR010953: IPR019810; KEGG: nml:Namu_4703 citrate synthase I; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: Citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family.
  
  
 0.505
ADU49641.1
COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR014757: IPR002563; KEGG: cgt:cgR_2302 hypothetical protein; PFAM: flavin reductase domain protein FMN-binding; SPTR: Putative uncharacterized protein; PFAM: Flavin reductase like domain.
  
    0.505
ADU46914.1
Transcriptional regulator, IclR family; COGs: COG1414 Transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: rop:ROP_71890 putative IclR family transcriptional regulator; PFAM: regulatory protein IclR; SMART: regulatory protein IclR; SPTR: Putative IclR family transcriptional regulator; PFAM: IclR helix-turn-helix domain.
  
    0.501
ADU47362.1
Transcriptional regulator, IclR family; COGs: COG1414 Transcriptional regulator; InterPro IPR005471: IPR014757; KEGG: tfu:Tfu_0849 regulatory proteins, IclR; PFAM: Transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; SPTR: Regulatory proteins, IclR; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator.
  
    0.501
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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