STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47357.1COGs: COG2225 Malate synthase; InterPro IPR011076: IPR006252: IPR019830; KEGG: kfl:Kfla_0722 malate synthase A; PFAM: Malate synthase family protein; PRIAM: Malate synthase; SPTR: Malate synthase; TIGRFAM: malate synthase A; PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family. (526 aa)    
Predicted Functional Partners:
ADU47249.1
Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.985
ADU47358.1
D-lactate dehydrogenase (cytochrome); COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR016166: IPR006094: IPR004113; KEGG: sen:SACE_6366 glycolate oxidase subunit; PFAM: FAD linked oxidase domain protein; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: Glycolate oxidase subunit; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD.
  
 
 0.980
ADU47359.1
FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR016166: IPR006094: IPR004113; KEGG: tcu:Tcur_3272 FAD linked oxidase domain protein; PFAM: FAD linked oxidase domain protein; SPTR: FAD linked oxidase domain protein; PFAM: FAD binding domain.
  
 
 0.980
ADU47360.1
Protein of unknown function DUF224 cysteine-rich region domain protein; COGs: COG0247 Fe-S oxidoreductase; InterPro IPR017896: IPR004017: IPR012257: IPR017900; KEGG: sen:SACE_6364 glycolate oxidase iron-sulfur subunit; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Glycolate oxidase iron-sulfur subunit; PFAM: Cysteine-rich domain.
  
 
 0.980
ADU46915.1
COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: cai:Caci_4507 acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Acetate/CoA ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme.
   
 0.953
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.953
ADU47292.1
COGs: COG0372 Citrate synthase; InterPro IPR002020: IPR019810; KEGG: sma:SAV_3859 citrate synthase 2; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: Citrate (Si)-synthase; PFAM: Citrate synthase; Belongs to the citrate synthase family.
   
 0.953
ADU47355.1
COGs: COG0372 Citrate synthase; InterPro IPR002020: IPR010953: IPR019810; KEGG: nml:Namu_4703 citrate synthase I; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: Citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family.
   
 0.953
ADU49111.1
COGs: COG0372 Citrate synthase; InterPro IPR010953: IPR002020: IPR019810; KEGG: rsa:RSal33209_1176 citrate synthase; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: Citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family.
   
 0.953
ADU49201.1
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.937
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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