STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47373.1Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847: IPR005119; KEGG: scl:sce0177 LysR family transcriptional regulator; PFAM: regulatory protein LysR; LysR substrate-binding; SPTR: HTH-type transcriptional regulator syrM; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family. (311 aa)    
Predicted Functional Partners:
ADU47371.1
Hypothetical protein; InterPro IPR017896; KEGG: ach:Achl_0766 hypothetical protein; SPTR: Predicted protein; PFAM: Protein of unknown function (DUF1271).
 
     0.913
ADU47370.1
COGs: COG2124 Cytochrome P450; InterPro IPR002397: IPR017973: IPR001128: IPR017972; KEGG: ach:Achl_0767 cytochrome P450; PFAM: cytochrome P450; SPTR: Cytochrome P450 hydroxylase; PFAM: Cytochrome P450.
 
     0.908
ADU47372.1
COGs: COG1251 NAD(P)H-nitrite reductase; InterPro IPR013027: IPR000103; KEGG: ach:Achl_0765 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Ferredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
 
     0.823
ADU47369.1
InterPro IPR001647; KEGG: mjl:Mjls_5623 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: Transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family.
 
 
   0.662
ADU47378.1
Monooxygenase FAD-binding protein; COGs: COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductase; InterPro IPR003042: IPR002938; KEGG: ach:Achl_0771 monooxygenase FAD-binding; PFAM: monooxygenase FAD-binding; SPTR: Predicted protein; PFAM: FAD binding domain.
  
   
 0.639
ADU47380.1
Beta-lactamase domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: ach:Achl_0773 beta-lactamase domain protein; SPTR: Predicted protein; PFAM: Metallo-beta-lactamase superfamily.
  
    0.612
ADU48157.1
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: kfl:Kfla_3074 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Putative glutamate synthase (NADPH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
  
  
 0.586
ADU47381.1
Hydrolase CocE/NonD family protein; COGs: COG2936 acyl esterase; InterPro IPR013736: IPR005674; KEGG: ach:Achl_0774 X-Pro dipeptidyl-peptidase domain protein; PFAM: X-Pro dipeptidyl-peptidase domain protein; SPTR: X-Pro dipeptidyl-peptidase domain protein; TIGRFAM: hydrolase CocE/NonD family protein; PFAM: X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; X-Pro dipeptidyl-peptidase (S15 family); TIGRFAM: putative hydrolase, CocE/NonD family.
  
     0.579
ADU47376.1
Aryldialkylphosphatase; COGs: COG1735 metal-dependent hydrolase with the TIM-barrel fold; InterPro IPR001559; KEGG: ach:Achl_0769 aryldialkylphosphatase; PFAM: aryldialkylphosphatase; SPTR: Predicted protein; PFAM: Phosphotriesterase family; Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
  
   
 0.497
ADU47377.1
Aryldialkylphosphatase; COGs: COG1735 metal-dependent hydrolase with the TIM-barrel fold; InterPro IPR001559; KEGG: ach:Achl_0770 aryldialkylphosphatase; PFAM: aryldialkylphosphatase; SPTR: Parathion hydrolase; PFAM: Phosphotriesterase family.
  
   
 0.485
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: low (20%) [HD]