STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47413.1Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (283 aa)    
Predicted Functional Partners:
ADU48037.1
Protein of unknown function DUF152; COGs: COG1496 conserved hypothetical protein; InterPro IPR003730; KEGG: kra:Krad_3195 protein of unknown function DUF152; PFAM: protein of unknown function DUF152; SPTR: Putative uncharacterized protein; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: uncharacterized protein, YfiH family; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.903
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
 0.878
ADU47412.1
SAF domain protein; InterPro IPR013974; KEGG: kra:Krad_3695 SAF domain protein; PFAM: SAF domain protein; SPTR: SAF domain protein; PFAM: SAF domain.
       0.781
mscL
Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
       0.585
ADU47415.1
Potassium/proton antiporter, CPA1 family; COGs: COG3263 NhaP-type Na+/H+ and K+/H+ antiporter with a unique C-terminal domain; InterPro IPR006037: IPR006153; KEGG: kra:Krad_3692 potassium/proton antiporter; PFAM: sodium/hydrogen exchanger; TrkA-C domain protein; SPTR: Cell volume regulation protein CvrA; PFAM: TrkA-C domain; Sodium/hydrogen exchanger family; TC 2.A.36.
  
    0.574
ADU47414.1
Regulatory protein, FmdB family; COGs: COG2331 conserved hypothetical protein; InterPro IPR013429; KEGG: ske:Sked_30590 putative regulatory protein, FmdB family; PFAM: Putative regulatory protein FmdB; SPTR: Putative regulatory protein, FmdB family; TIGRFAM: regulatory protein, FmdB family; manually curated; PFAM: Zinc ribbon domain; TIGRFAM: putative regulatory protein, FmdB family.
       0.571
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.568
ADU47379.1
Alpha/beta hydrolase fold-3 domain protein; COGs: COG0657 Esterase/lipase; InterPro IPR002168; KEGG: ach:Achl_0772 alpha/beta hydrolase fold-3 domain protein; SPTR: Esterase/lipase; PFAM: alpha/beta hydrolase fold.
 
  
 0.521
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.