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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47413.1Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (283 aa)    
Predicted Functional Partners:
ADU46758.1
Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: bja:blr0249 hypothetical protein; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family.
  
 
 0.911
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
 0.890
ADU47412.1
SAF domain protein; InterPro IPR013974; KEGG: kra:Krad_3695 SAF domain protein; PFAM: SAF domain protein; SPTR: SAF domain protein; PFAM: SAF domain.
       0.784
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.614
mscL
Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
       0.601
ADU47415.1
Potassium/proton antiporter, CPA1 family; COGs: COG3263 NhaP-type Na+/H+ and K+/H+ antiporter with a unique C-terminal domain; InterPro IPR006037: IPR006153; KEGG: kra:Krad_3692 potassium/proton antiporter; PFAM: sodium/hydrogen exchanger; TrkA-C domain protein; SPTR: Cell volume regulation protein CvrA; PFAM: TrkA-C domain; Sodium/hydrogen exchanger family; TC 2.A.36.
  
    0.594
ADU47414.1
Regulatory protein, FmdB family; COGs: COG2331 conserved hypothetical protein; InterPro IPR013429; KEGG: ske:Sked_30590 putative regulatory protein, FmdB family; PFAM: Putative regulatory protein FmdB; SPTR: Putative regulatory protein, FmdB family; TIGRFAM: regulatory protein, FmdB family; manually curated; PFAM: Zinc ribbon domain; TIGRFAM: putative regulatory protein, FmdB family.
       0.587
ADU47379.1
Alpha/beta hydrolase fold-3 domain protein; COGs: COG0657 Esterase/lipase; InterPro IPR002168; KEGG: ach:Achl_0772 alpha/beta hydrolase fold-3 domain protein; SPTR: Esterase/lipase; PFAM: alpha/beta hydrolase fold.
 
    0.515
ADU47797.1
COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: bfa:Bfae_20890 glycosyl transferase; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase; manually curated; PFAM: Glycosyl transferase family 2.
     
 0.456
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.441
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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