STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47415.1Potassium/proton antiporter, CPA1 family; COGs: COG3263 NhaP-type Na+/H+ and K+/H+ antiporter with a unique C-terminal domain; InterPro IPR006037: IPR006153; KEGG: kra:Krad_3692 potassium/proton antiporter; PFAM: sodium/hydrogen exchanger; TrkA-C domain protein; SPTR: Cell volume regulation protein CvrA; PFAM: TrkA-C domain; Sodium/hydrogen exchanger family; TC 2.A.36. (523 aa)    
Predicted Functional Partners:
ADU47414.1
Regulatory protein, FmdB family; COGs: COG2331 conserved hypothetical protein; InterPro IPR013429; KEGG: ske:Sked_30590 putative regulatory protein, FmdB family; PFAM: Putative regulatory protein FmdB; SPTR: Putative regulatory protein, FmdB family; TIGRFAM: regulatory protein, FmdB family; manually curated; PFAM: Zinc ribbon domain; TIGRFAM: putative regulatory protein, FmdB family.
       0.827
ADU47416.1
Peptidase S45 penicillin amidase; COGs: COG2366 Protein related to penicillin acylase; InterPro IPR002692: IPR014395: IPR002034; KEGG: cfl:Cfla_0835 peptidase S45 penicillin amidase; PFAM: peptidase S45 penicillin amidase; SPTR: Penicillin amidase; PFAM: Penicillin amidase.
       0.645
ADU47413.1
Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage.
  
    0.594
mscL
Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
     
 0.518
ADU47412.1
SAF domain protein; InterPro IPR013974; KEGG: kra:Krad_3695 SAF domain protein; PFAM: SAF domain protein; SPTR: SAF domain protein; PFAM: SAF domain.
       0.494
ADU48442.1
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR006036: IPR003148: IPR006037; KEGG: ske:Sked_16160 K+ transport system, NAD-binding component; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: Putative potassium uptake protein; PFAM: TrkA-N domain; TrkA-C domain.
 
   
 0.434
ADU48441.1
TrkA-N domain protein; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR006036: IPR003148: IPR006037; KEGG: kfl:Kfla_3761 TrkA-N domain protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: Potassium uptake protein; manually curated; PFAM: TrkA-N domain; TrkA-C domain.
 
   
 0.421
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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