STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47424.1Protein of unknown function DUF72; COGs: COG1801 conserved hypothetical protein; InterPro IPR002763; KEGG: rha:RHA1_ro02437 hypothetical protein; PFAM: protein of unknown function DUF72; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF72. (276 aa)    
Predicted Functional Partners:
ADU47423.1
Protein of unknown function UPF0118; COGs: COG0628 permease; InterPro IPR002549; KEGG: kfl:Kfla_5640 protein of unknown function UPF0118; PFAM: protein of unknown function UPF0118; SPTR: Integral membrane protein; PFAM: Domain of unknown function DUF20.
       0.590
ADU47425.1
KEGG: nca:Noca_2699 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
       0.558
ADU50001.1
COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR012310: IPR012309; KEGG: nml:Namu_0826 ATP-dependent DNA ligase; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; SPTR: DNA ligase; PFAM: ATP dependent DNA ligase domain; ATP dependent DNA ligase C terminal region.
 
    0.539
ADU48409.1
DNA polymerase LigD, polymerase domain protein; COGs: COG3285 eukaryotic-type DNA primase; InterPro IPR002755: IPR014145; KEGG: amd:AMED_4612 ATP-dependent DNA ligase; PFAM: DNA primase small subunit; SPTR: Putative uncharacterized protein; TIGRFAM: DNA polymerase LigD, polymerase domain protein; PFAM: Eukaryotic and archaeal DNA primase small subunit; TIGRFAM: DNA ligase D; DNA polymerase LigD, polymerase domain.
 
    0.445
ADU47172.1
DNA polymerase LigD, polymerase domain protein; COGs: COG3285 eukaryotic-type DNA primase; InterPro IPR002755: IPR014145; KEGG: nca:Noca_1237 ATP dependent DNA ligase; PFAM: DNA primase small subunit; SPTR: DNA ligase; TIGRFAM: DNA polymerase LigD, polymerase domain protein; TIGRFAM: DNA polymerase LigD, polymerase domain.
 
    0.441
ADU47171.1
DNA polymerase LigD, ligase domain protein; COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR012310: IPR014146: IPR016059; KEGG: cfl:Cfla_1903 DNA polymerase LigD, ligase domain protein; PFAM: ATP dependent DNA ligase; SPTR: DNA ligase; TIGRFAM: DNA polymerase LigD, ligase domain protein; PFAM: ATP dependent DNA ligase domain; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA polymerase LigD, ligase domain.
 
    0.430
ku
DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
    0.428
ADU47426.1
Alcohol dehydrogenase zinc-binding domain protein; COGs: COG1064 Zn-dependent alcohol dehydrogenase; InterPro IPR013154: IPR013149: IPR002328; KEGG: mjl:Mjls_1690 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: Alcohol dehydrogenase, zinc-binding domain protein; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase.
       0.424
ADU47427.1
KEGG: tbi:Tbis_0638 hypothetical protein.
       0.423
ADU50000.1
COGs: COG3285 eukaryotic-type DNA primase; InterPro IPR002755; KEGG: kse:Ksed_15620 DNA polymerase LigD, polymerase domain; PFAM: DNA primase small subunit; SPTR: DNA ligase; TIGRFAM: DNA polymerase LigD, polymerase domain.
 
    0.401
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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