STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Experiments
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[Homology]
Score
ADU47435.1Hydrolase, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR001130: IPR012278: IPR015991; KEGG: kse:Ksed_03330 hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; SPTR: Putative uncharacterized protein; TIGRFAM: hydrolase, TatD family; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family. (290 aa)    
Predicted Functional Partners:
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 
 0.904
rsmA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
  
 0.786
ADU47436.1
Transglycosylase-like domain protein; COGs: COG3583 conserved hypothetical protein; InterPro IPR011098: IPR007137: IPR010618; KEGG: kfl:Kfla_5728 transglycosylase domain protein; PFAM: Transglycosylase-like domain protein; G5 domain protein; protein of unknown function DUF348; SPTR: Putative uncharacterized protein; PFAM: Transglycosylase-like domain; Domain of unknown function (DUF348); G5 domain.
     
 0.695
ispE
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
     
 0.635
rsmI
Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
  
    0.510
ADU47433.1
Peroxiredoxin, OsmC subfamily; COGs: COG1764 redox protein regulator of disulfide bond formation; InterPro IPR003718: IPR019904; KEGG: nca:Noca_1377 OsmC family protein; PFAM: OsmC family protein; SPTR: Putative ATP/GTP-binding protein; TIGRFAM: peroxiredoxin, OsmC subfamily; PFAM: OsmC-like protein; TIGRFAM: peroxiredoxin, OsmC subfamily.
       0.502
tsaD
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
   
 0.502
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
  
 0.453
ADU50122.1
Membrane protein insertase, YidC/Oxa1 family; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708: IPR020001: IPR000215; KEGG: cfl:Cfla_3727 membrane protein insertase, YidC/Oxa1 family; PFAM: 60 kDa inner membrane insertion protein; SPTR: Putative inner membrane protein translocase component YidC; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain.
 
  
 0.447
rsmH
S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
 
     0.429
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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