STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47467.1Regulatory protein LuxR; InterPro IPR000792; KEGG: kfl:Kfla_5405 transcriptional regulator, TrmB; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: Transcriptional regulator, TrmB; PFAM: Sugar-specific transcriptional regulator TrmB; Bacterial regulatory proteins, luxR family. (336 aa)    
Predicted Functional Partners:
ADU47468.1
Peptidase S8 and S53 subtilisin kexin sedolisin; COGs: COG1404 Subtilisin-like serine protease; InterPro IPR010259: IPR000209: IPR017909; KEGG: dge:Dgeo_0978 peptidase S8/S53 subtilisin kexin sedolisin; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proteinase inhibitor I9 subtilisin propeptide; SPTR: Thermophilic protease; PFAM: Peptidase inhibitor I9; Subtilase family.
 
    0.640
ADU49321.1
Polysulphide reductase NrfD; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017896: IPR005614: IPR017900; KEGG: nca:Noca_2933 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: Polysulphide reductase NrfD; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain; Polysulphide reductase, NrfD.
  
    0.572
ADU49348.1
YD repeat protein; InterPro IPR003587: IPR006141: IPR006530; KEGG: stp:Strop_1054 YD repeat-containing protein; SMART: Hedgehog/intein hint domain protein; SPTR: YD repeat protein; TIGRFAM: YD repeat protein; PFAM: Protein of unknown function (DUF1557); TIGRFAM: RHS repeat-associated core domain.
  
    0.556
ADU49815.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003018: IPR011712: IPR003594; KEGG: saq:Sare_1529 GAF sensor signal transduction histidine kinase; PFAM: GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: GAF domain protein; SPTR: GAF sensor signal transduction histidine kinase; PFAM: Histidine kinase; GAF domain.
  
 
 0.546
ADU49210.1
InterPro IPR001845; KEGG: xce:Xcel_0321 transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: Putative ArsR-family transcriptional regulator; PFAM: Bacterial regulatory protein, arsR family.
  
  
 0.496
ADU46986.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 005561: IPR013656: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: ami:Amir_3954 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; PAS fold domain protein; ANTAR domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Multi [...]
  
 
 0.489
ADU47466.1
Cystathionine beta-synthase; COGs: COG0031 Cysteine synthase; InterProIPR001926: IPR000644: IPR005829: IPR001216: IPR 005857; KEGG: rha:RHA1_ro05843 cystathionine beta-synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; CBS domain containing protein; SMART: CBS domain containing protein; SPTR: Putative cystathionine beta-synthase; TIGRFAM: cystathionine beta-synthase; PFAM: CBS domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: cystathionine beta-synthase.
     
 0.481
ADU47498.1
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR007168: IPR003594; KEGG: art:Arth_2999 putative signal transduction histidine kinase; PFAM: PspC domain protein; ATP-binding region ATPase domain protein; SPTR: Putative signal transduction histidine kinase; PFAM: PspC domain.
  
 
 0.456
ADU49802.1
OsmC family protein; COGs: COG1765 redox protein regulator of disulfide bond formation; InterPro IPR003718; KEGG: sma:SAV_2602 hypothetical protein; PFAM: OsmC family protein; SPTR: OsmC family protein; PFAM: OsmC-like protein.
  
     0.455
ADU47365.1
KEGG: stp:Strop_1593 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.431
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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