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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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Score
ADU47478.1COGs: COG0657 Esterase/lipase; InterPro IPR002168; KEGG: mkm:Mkms_0324 alpha/beta hydrolase domain-containing protein; SPTR: Alpha/beta hydrolase fold-3; PFAM: alpha/beta hydrolase fold. (304 aa)    
Predicted Functional Partners:
ADU47475.1
COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220: IPR020625; KEGG: sro:Sros_2475 putative dihydropicolinate synthase family protein; PFAM: dihydrodipicolinate synthetase; SPTR: Dihydrodipicolinate synthetase; PFAM: Dihydrodipicolinate synthetase family; Belongs to the DapA family.
 
   
 0.821
ADU47473.1
Oligopeptide/dipeptide ABC transporter, ATPase subunit; COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterProIPR000515: IPR003439: IPR013563: IPR017871: IPR 010066: IPR003593; KEGG: sma:SAV_5609 ABC transporter permease protein; PFAM: ABC transporter related; binding-protein-dependent transport systems inner membrane component; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: Oligopeptide/dipeptide ABC transporter, ATPase subunit; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transpor [...]
       0.785
nanE
N-acylglucosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
     
 0.784
ADU47474.1
Oligopeptide/dipeptide ABC transporter, ATPase subunit; COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterProIPR003439: IPR013563: IPR017871: IPR010066: IPR 003593; KEGG: sma:SAV_5608 ABC transporter ATP-binding protein; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: Oligopeptide/dipeptide ABC transporter, ATPase subunit; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopept [...]
       0.776
ADU47476.1
ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600: IPR002328; KEGG: bcv:Bcav_3770 ROK family protein; PFAM: ROK family protein; SPTR: ROK family protein; PFAM: ROK family.
       0.776
ADU47472.1
COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: rer:RER_09420 ABC transporter permease protein; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.
       0.773
ADU46997.1
FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR017941: IPR006076; KEGG: nda:Ndas_1353 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; Rieske [2Fe-2S] iron-sulphur domain; SPTR: FAD dependent oxidoreductase; PFAM: Rieske [2Fe-2S] domain; FAD dependent oxidoreductase.
 
 
 0.770
ADU47471.1
Extracellular solute-binding protein family 5; COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR019546: IPR000914: IPR017909: IPR006311; KEGG: sgr:SGR_6426 putative ABC transporter substrate-binding protein; PFAM: extracellular solute-binding protein family 5; Twin-arginine translocation pathway, signal sequence, subgroup; SPTR: Extracellular solute-binding protein family 5; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence.
       0.539
acpP
Phosphopantetheine-binding protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
   
 
 0.484
ADU47370.1
COGs: COG2124 Cytochrome P450; InterPro IPR002397: IPR017973: IPR001128: IPR017972; KEGG: ach:Achl_0767 cytochrome P450; PFAM: cytochrome P450; SPTR: Cytochrome P450 hydroxylase; PFAM: Cytochrome P450.
  
 0.414
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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