Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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ADU47498.1COGs: COG4585 Signal transduction histidine kinase; InterPro IPR007168: IPR003594; KEGG: art:Arth_2999 putative signal transduction histidine kinase; PFAM: PspC domain protein; ATP-binding region ATPase domain protein; SPTR: Putative signal transduction histidine kinase; PFAM: PspC domain. (483 aa)    
Predicted Functional Partners:
ADU47497.1
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789: IPR000792; KEGG: bcv:Bcav_3033 two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; SMART: regulatory protein LuxR; response regulator receiver; SPTR: Putative two-component system DNA-binding response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; TIGRFAM: RNA polymerase sigma factor, sigma-70 family.
 
 
 0.947
ADU46986.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 005561: IPR013656: IPR003661: IPR003594: IPR013767: IPR004358; KEGG: ami:Amir_3954 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; PAS fold domain protein; ANTAR domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Multi [...]
  
 
 0.940
ADU47499.1
PspC domain protein; InterPro IPR007168; KEGG: art:Arth_3000 phage shock protein C, PspC; PFAM: PspC domain protein; SPTR: Putative uncharacterized protein; PFAM: PspC domain.
 
  
 0.899
ADU47976.1
Transcriptional regulator, LuxR family; COGs: COG3899 ATPase; InterPro IPR000792: IPR019734; KEGG: sti:Sthe_2247 transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; Tetratricopeptide repeat; SPTR: Transcriptional regulator, LuxR family; PFAM: Bacterial regulatory proteins, luxR family.
 
 
 0.689
ADU46802.1
Membrane protein of unknown function; InterPro IPR007165; KEGG: kse:Ksed_02330 predicted membrane protein; PFAM: membrane protein of unknown function; SPTR: Predicted membrane protein; PFAM: Membrane protein of unknown function.
  
    0.626
ADU47506.1
Transcriptional regulator, LuxR family; COGs: COG3899 ATPase; InterPro IPR000792; KEGG: tcu:Tcur_0848 transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: Transcriptional regulator, LuxR family; PFAM: Bacterial regulatory proteins, luxR family.
 
 
 0.563
ADU47029.1
Colicin V production protein; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR003825: IPR001254: IPR001940; KEGG: kra:Krad_0420 peptidase S1 and S6 chymotrypsin/Hap; PFAM: Colicin V production protein; peptidase S1 and S6 chymotrypsin/Hap; SPTR: Peptidase S1 and S6 chymotrypsin/Hap; PFAM: Trypsin; Colicin V production protein.
  
  
 0.550
ADU47270.1
Peptidase S1 and S6 chymotrypsin/Hap; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478: IPR001940: IPR001254; KEGG: bcv:Bcav_3234 2-alkenal reductase; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Trypsin-like serine protease; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF).
  
  
 0.550
ADU49098.1
Peptidase S1 and S6 chymotrypsin/Hap; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478: IPR001940: IPR001254; KEGG: bcv:Bcav_2919 peptidase S1 and S6 chymotrypsin/Hap; PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: PDZ/DHR/GLGF domain protein; SPTR: Putative protease; PFAM: Trypsin.
  
  
 0.550
ADU50021.1
Peptidase S1 and S6 chymotrypsin/Hap; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001254: IPR001940; KEGG: cfl:Cfla_1619 peptidase S1 and S6 chymotrypsin/Hap; PFAM: peptidase S1 and S6 chymotrypsin/Hap; SPTR: Peptidase S1 and S6 chymotrypsin/Hap; PFAM: Trypsin.
  
  
 0.550
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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