STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU47501.1Endothelin-converting enzyme; COGs: COG3590 metalloendopeptidase; InterPro IPR008753: IPR018497; KEGG: cfl:Cfla_1374 neprilysin; PFAM: peptidase M13; Peptidase M13, neprilysin-like; PRIAM: Endothelin-converting enzyme 1; SPTR: Putative peptidase; PFAM: Peptidase family M13. (654 aa)    
Predicted Functional Partners:
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
 
      0.571
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.558
ADU47267.1
Membrane alanyl aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782: IPR012778; KEGG: kse:Ksed_21360 aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; SPTR: Putative aminopeptidase; TIGRFAM: aminopeptidase N; PFAM: Peptidase family M1; Domain of unknown function (DUF3358); TIGRFAM: aminopeptidase N, Streptomyces lividans type.
 
   
 0.552
ADU47877.1
Membrane alanyl aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR012778: IPR014782: IPR005829; KEGG: kse:Ksed_09020 aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; PRIAM: Membrane alanyl aminopeptidase; SPTR: Aminopeptidase N; TIGRFAM: aminopeptidase N; PFAM: Domain of unknown function (DUF3358); Peptidase family M1; TIGRFAM: aminopeptidase N, Streptomyces lividans type.
 
   
 0.550
ruvB
Holliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
   
    0.513
pepA
Peptidase M17 leucyl aminopeptidase domain protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
      
 0.461
ADU48197.1
COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR020832: IPR020830: IPR020831: IPR020828: IPR 020829: IPR006424; KEGG: kfl:Kfla_3261 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: Glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydroge [...]
   
  
 0.458
ADU50041.1
phospholipase/Carboxylesterase; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR003140; KEGG: kfl:Kfla_4635 peptidase S9 prolyl oligopeptidase active site domain protein; PFAM: phospholipase/Carboxylesterase; SPTR: Peptidase S9 prolyl oligopeptidase active site domain protein; PFAM: Prolyl oligopeptidase family.
  
    0.456
ADU48880.1
COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR006424: IPR020830: IPR020828: IPR020829: IPR 020832; KEGG: aau:AAur_2411 glyceraldehyde-3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Gl [...]
   
  
 0.450
ADU47499.1
PspC domain protein; InterPro IPR007168; KEGG: art:Arth_3000 phage shock protein C, PspC; PFAM: PspC domain protein; SPTR: Putative uncharacterized protein; PFAM: PspC domain.
       0.443
Your Current Organism:
Intrasporangium calvum
NCBI taxonomy Id: 710696
Other names: I. calvum DSM 43043, Intrasporangium calvum DSM 43043, Intrasporangium calvum IFO 12989, Intrasporangium calvum NBRC 12989, Intrasporangium calvum str. DSM 43043, Intrasporangium calvum strain DSM 43043
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